Project/Area Number |
20791111
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Urology
|
Research Institution | Okayama University |
Principal Investigator |
ARAKI Motoo Okayama University, 岡山大学病院, 助教 (90467746)
|
Research Collaborator |
KAWAUCHI Keiichiro 岡山大学, 大学院・医歯薬学総合研究科, 大学院生
HIROHATA Satoshi 岡山大学, 大学院・医歯薬学総合研究科, 助教 (90332791)
NINOMIYA Yoshifumi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70126241)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 腎虚血再潅流障害 / ドキシサイクリン / 細胞外マトリックス(MMP) / MMP阻害薬 / 腎移植 / MMP |
Research Abstract |
We established murine renal ischemia reperfusion injury (IRI) model. Renal hilums of B6 mouse was clumped for 45 minutes under anesthesia. Body temperature was kept on 32℃. We have identified reduced IRI by measuring serum creatinine level and histopathology.
|