Chemoprevention and chemotherapy for prostate cancer mouse model with valproic acid

• Project/Area Number: 20791112
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Urology
• Research Institution: Nagasaki University
• Principal Investigator: ONITA Toru Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (50452850)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 前立腺癌 / マウスモデル / バルプロ酸 / 化学予防、治療

Research Abstract

The purpose of this study was to evaluate the efficacy of valproic acid to prostate cancer. Valproic acid was administered to the prostate cancer mouse models and compared the removed prostate with the prostate removed from control mice. But no difference was found between these two groups both macroscopically and microscopically.