Fundamental researches for clinical application of the fetal gene therapy using an adeno-associated virus vector
Project/Area Number |
20791131
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Obstetrics and gynecology
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Research Institution | University of Tsukuba |
Principal Investigator |
OGURA Tsuyoshi University of Tsukuba, 大学院・人間総合科学研究科, 講師 (40451702)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Keywords | アデノ随伴ウイルス(AAV)ベクター / 血清型 / 胎児遺伝子治療 / AAV / 妊婦 / 抗体保有率 |
Research Abstract |
"Gene therapy" treats disease at a genetic level.An AAV vector attracts attention from a safe aspect, and there are various models (serotype).I investigated serotype of the AAV vector which was suitable for fetal gene therapy.It became clear that an AAV1 type vector was suitable.Clinical application of fetal gene therapy was expected by developing these results.
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Report
(3 results)
Research Products
(1 results)