Functional analysis of oocyte-specific linker histone in the process of primate oocyte maturation.
| Project/Area Number |
20791164
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Keio University |
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Principal Investigator |
ASAI Satoshi Keio University, 医学部, 助教 (70383867)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 卵子特異的リンカーヒストン / H1FOO / リン酸化 / 卵子成熟 / 減数分裂 / 生殖 / ノックアウトマウス / 卵子形成 / Hlfoo |
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| Research Abstract |
Analysis of knockout mouse revealed that the deletion of oocyte specific linker histone, H1FOO has no effect of oogenesis and fertility. This may result from the existence of compensatory mechanism for H1FOO.
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Report
(3 results)
Research Products
(1 results)
