Functional analysis of oocyte-specific linker histone in the process of primate oocyte maturation.

Research Project

Project/Area Number	20791164
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Obstetrics and gynecology
Research Institution	Keio University
Principal Investigator	ASAI Satoshi Keio University, 医学部, 助教 (70383867)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000) Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	卵子特異的リンカーヒストン / H1FOO / リン酸化 / 卵子成熟 / 減数分裂 / 生殖 / ノックアウトマウス / 卵子形成 / Hlfoo
Research Abstract	Analysis of knockout mouse revealed that the deletion of oocyte specific linker histone, H1FOO has no effect of oogenesis and fertility. This may result from the existence of compensatory mechanism for H1FOO.

Report

(3 results)