Regulation of placenta specific transcription factor GCMa/1 expression

Research Project

Project/Area Number	20791172
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Obstetrics and gynecology
Research Institution	Kinjo Gakuin University
Principal Investigator	YASUI Yuko Kinjo Gakuin University, 薬学部, 助教 (80434554)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000) Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords	発現制御 / 胎盤 / GCMa / 1 / シグナル伝達 / 転写因子
Research Abstract	Glial cells missing a/1(GCMa/1)is a placenta specific transcription factor and essential for placental development and function. In this study, we investigated signal transduction mechanisms in regulation of GCMa/1 expression. We demonstrated that GCMa/1 expression is dependent upon PKC signaling pathway in addition to that of cAMP/PKA.

Report

(3 results)