Genetic analysis of progressive or delayed onset hearing loss in early childhood.
| Project/Area Number |
20791194
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Okayama University |
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Principal Investigator |
KATAOKA Yuko Okayama University, 岡山大学病院, 助教 (10362972)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 進行性難聴 / 遅発性難聴 / 難聴遺伝子 / 前庭水管拡大症 / 先天性サイトメガロウイルス感染症 / auditory neuropathy / 新生児聴覚スクリーニング検査 / Auditory Neuropathy |
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| Research Abstract |
We classified progressive or delayed onset hearing loss in the early childhood. We investigated deafness gene mutation and congenital cytomegalovirus infection of progressive or delayed onset hearing loss children, and in addition, analyzed OTOF of a child with auditory neuropathy. Some of them had enlarged vestibule aqueduct, and one of them had SLC26A4 mutation. There were children who had diagnosis of congenital cytomegalovirus infection, but someone deteriorate their hearing in early childhood without any risk factors. A case with auditory neuropathy didn't have OTOF gene mutation. We started the screening of deafness gene mutation by the invader method in our hospital in December, 2009, and we need to increase cases and investigate them more in the future.
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Report
(3 results)
Research Products
(8 results)
