The role of tight junction proteins in human pharyngeal carcinoma
| Project/Area Number |
20791208
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
KONDOH Atsushi Sapporo Medical University, 医学部, 助教 (40457718)
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| Research Collaborator |
HIMI Tetsuo 札幌医科大学, 医学部, 教授 (90181114)
SAWADA Norimasa 札幌医科大学, 医学部, 教授 (30154149)
KAMEKURA Ryuta 札幌医科大学, 医学部, 研究員 (70404697)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | タイト結合 / 咽頭癌 / 腫瘍浸潤 / HPV |
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| Research Abstract |
In human tonsillar squamous cell carcinoma, the expression of claudin-7 and tricellulin was weak or absent, whereas claudin-1 was observed strong expression. At the invasive front, claudin-1 was stronger expression. There were not significant relationships between the tight junction expressions and HPV status.
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Report
(3 results)
Research Products
(13 results)
