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Analysis of factors contributing the onset of allergic rhinitis in children~Strategy to early intervention

Research Project

Project/Area Number 20791209
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionSapporo Medical University

Principal Investigator

KANAIZUMI Etsuko  Sapporo Medical University, 医学部, 助教 (60404688)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords鼻アレルギー / 小児 / 早期介入
Research Abstract

The purpose of this study is to predict contributing factors of the onset of allergic rhinitis in children. These analyses are help to decide about how to intervene in allergic rhinitis in children. We have investigated a variety of items for each period from infancy, and examined the correlation between the results and nasal drop eosinophils. But, because of the prospective cohort study, some children still do not develop allergic disease. The future is expected to increase in severity of symptoms and the sensitizing antigen in these children. Therefore, we plan to observe the progress of the children in the future.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2010 2009

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (13 results)

  • [Journal Article] 通年性鼻アレルギー症例に対する免疫療法とレーザー手術の併用療法2010

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Journal Title

      日本レーザー医学会誌 Vol.31, No2

      Pages: 131-134

    • NAID

      10026579082

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Expression and localization of the muscarinic receptor in human nasal mucosa.2010

    • Author(s)
      Shirasaki H, Kanaizumi E, Himi T.
    • Journal Title

      Proceedung of Airway secretion Research. 12

      Pages: 1-5

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Expression and localization of the muscarinic receptor in human nasal mucosa.2010

    • Author(s)
      Shirasaki H, et al.
    • Journal Title

      Proceedung of Airway secretion Research

      Volume: 12 Pages: 1-5

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expession and localization of the muscarinic reseptor in human nasalmucosa.2010

    • Author(s)
      Shirasaki H, et al.
    • Journal Title

      Proceeding of Airway Secretion Research XII

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistchemical localization of the bradykinin B1 and B2 receptoers in human nasal mucosa.2009

    • Author(s)
      Shirasaki H, Kanaizumi E, Himi T.
    • Journal Title

      Mediators Inflamation.Volume 2009 8

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa.2009

    • Author(s)
      Shirasaki H, Kikuchi M, Kanaizumi E, Himi T.
    • Journal Title

      Ann Allergy Asthma Immunol. 102

      Pages: 110-115

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa.2009

    • Author(s)
      Shirasaki H, et al.
    • Journal Title

      Ann Allergy Asthma Immunol 102

      Pages: 110-115

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistchemical localization of the bradykinin B1 and B2 receptoers in human nasal mucosa.2009

    • Author(s)
      Shirasaki H, et al.
    • Journal Title

      Mediators Inflammation. Apr23

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] ヒト鼻粘膜におけるロイコトリエンE4受容体-P2Y12受容体の発現と局在2010

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第60回日本アレルギー学会秋季学術大会
    • Place of Presentation
      アレルギー東京
    • Year and Date
      2010-11-25
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト鼻粘膜におけるロイコトリエンE4受容体-P2Y12受容体の発現と局在2010

    • Author(s)
      白崎英明
    • Organizer
      第60回 日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Expression and localization of P2Y12 receptor in human nasal mucosa.2010

    • Author(s)
      Shirasaki H, Kanaizumi E, Himi T.
    • Organizer
      Annual Meeting American College of Allergy and Immunology.
    • Place of Presentation
      アメリカ、フェニックス
    • Year and Date
      2010-11-11
    • Related Report
      2010 Final Research Report
  • [Presentation] Expresssion and localization of P2Y12 receptor in human nasak mucosa2010

    • Author(s)
      Shirasaki H
    • Organizer
      Annual Meeting American College of Allergy and Immunology
    • Place of Presentation
      フェニックス、アメリカ
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 鼻アレルギー局所におけるTh1-Th2バランスに関する免疫組織学的検討2010

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第28回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      福井
    • Year and Date
      2010-02-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 鼻アレルギー局所におけるGATA-3、T-bet、RORγ陽性細胞に関する免疫組織学的検討2009

    • Author(s)
      白崎英明
    • Organizer
      第59回 日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Year and Date
      2009-10-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 鼻アレルギー局所におけるGATA-3、T-bet陽性細胞に関する検討2009

    • Author(s)
      白崎英明
    • Organizer
      第48回 日本鼻科学会
    • Place of Presentation
      島根
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト下鼻甲介粘膜におけるムスカリン受容体の発現と局在に関する免疫組織学的検討2009

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第29回気道分泌研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-25
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト下鼻甲介粘膜におけるムスカリン受容体の発現と局在に関する免疫組織学的検討2009

    • Author(s)
      白崎英明
    • Organizer
      第29回 気道分泌研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト下鼻甲介粘膜におけるムスカリン受容体の発現と局在2009

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第21回気道病態研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-07
    • Related Report
      2010 Final Research Report
  • [Presentation] 鼻アレルギー局所におけるGATA-3、T-bet, RORγ陽性細胞に関する免疫組織学的検討2009

    • Author(s)
      白崎英明、才川悦子、氷見徹夫
    • Organizer
      第59回日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Related Report
      2010 Final Research Report
  • [Presentation] 鼻アレルギー局所におけるGATA-3、T-bet陽性細胞に関する検討2009

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第48回日本鼻科学会
    • Place of Presentation
      島根
    • Related Report
      2010 Final Research Report
  • [Presentation] 人下鼻甲介粘膜と鼻茸におけるGRαとGRβ受容体の発現と局在2009

    • Author(s)
      白崎英明、金泉悦子、氷見徹夫
    • Organizer
      第27回日本耳鼻咽喉科免疫アレルギー学会
    • Place of Presentation
      千葉
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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