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Regeneration of corneal endothelium and corneal epithelium frominduced pluripotent stem cells.

Research Project

Project/Area Number 20791242
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionTohoku University

Principal Investigator

YOKOKURA Shunji  Tohoku University, 病院, 助教 (30400378)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
KeywordsiPS細胞 / 幹細胞 / 角膜内皮 / 角膜上皮
Research Abstract

induced pluripotent stem cells (iPS cells) were cultured with some medium, sorted and analyzed. These cultured cells differentiated to neural crest cells. These neural crest cells were sphere-cultured. There had been cells expressing corneal endothelial marker in these sphere-cultured cells.
On the other hand, iPS cells were cultured with the other medium, sorted and analyzed. These cultured cells differentiated to corneal epithelial progenitor cells and had potency of wound healing

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (10 results)

All 2009 2008

All Presentation (6 results) Book (4 results)

  • [Presentation] DSAEK(角膜内皮移植術)視力不良例の原因解析2009

    • Author(s)
      横倉俊二
    • Organizer
      第63回日本臨床眼科学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-10
    • Related Report
      2009 Final Research Report
  • [Presentation] DSAEK(角膜内皮移植術)術後視力不良例の原因解析2009

    • Author(s)
      横倉俊二
    • Organizer
      第62回日本臨床眼科学会
    • Place of Presentation
      福岡市
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 東北大学におけるアカントアメーバ角膜炎2009

    • Author(s)
      横倉俊二
    • Organizer
      第33回角膜カンファランス・第25回日本角膜移植学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-02-21
    • Related Report
      2009 Final Research Report
  • [Presentation] 東北大学病院におけるアカントアメーバ角膜炎2009

    • Author(s)
      横倉俊二
    • Organizer
      第33回角膜カンファランス・第25回日本角膜移植学会
    • Place of Presentation
      ザ・リッツカールトン大阪
    • Year and Date
      2009-02-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 角膜上皮異型性を伴った角膜上皮基底膜ジストロフィの1例2008

    • Author(s)
      横倉俊二
    • Organizer
      第62回日本臨床眼科学会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-24
    • Related Report
      2009 Final Research Report
  • [Presentation] 角膜上皮異型性を伴った角膜上皮基底膜ジストロフィの1例2008

    • Author(s)
      横倉俊二
    • Organizer
      第62回日本臨床眼科学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-10-24
    • Related Report
      2008 Annual Research Report
  • [Book] 新しい眼科「角膜内皮疾患を理解する」2009

    • Author(s)
      横倉俊二
    • Publisher
      メディカル葵出版
    • Related Report
      2009 Final Research Report
  • [Book] 眼科プラクティス「眼科レーザー治療」2009

    • Author(s)
      横倉俊二
    • Total Pages
      327
    • Publisher
      文光堂
    • Related Report
      2009 Final Research Report
  • [Book] あたらしい眼科2009年2月号「角膜内皮疾患を理解する」2009

    • Author(s)
      横倉俊二
    • Publisher
      メディカル葵出版
    • Related Report
      2008 Annual Research Report
  • [Book] 眼科プラクティス26「眼科レーザー治療」2009

    • Author(s)
      横倉俊二
    • Total Pages
      327
    • Publisher
      文光堂
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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