Regeneration of corneal endothelium and corneal epithelium frominduced pluripotent stem cells.
Project/Area Number |
20791242
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Ophthalmology
|
Research Institution | Tohoku University |
Principal Investigator |
YOKOKURA Shunji Tohoku University, 病院, 助教 (30400378)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | iPS細胞 / 幹細胞 / 角膜内皮 / 角膜上皮 |
Research Abstract |
induced pluripotent stem cells (iPS cells) were cultured with some medium, sorted and analyzed. These cultured cells differentiated to neural crest cells. These neural crest cells were sphere-cultured. There had been cells expressing corneal endothelial marker in these sphere-cultured cells. On the other hand, iPS cells were cultured with the other medium, sorted and analyzed. These cultured cells differentiated to corneal epithelial progenitor cells and had potency of wound healing
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Report
(3 results)
Research Products
(10 results)