The effect of amylase-binding protein on formation of secretory granules in rat parotid gland.
| Project/Area Number |
20791363
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional basic dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
KATO Osamu Nihon University, 松戸歯学部, 講師 (70349968)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 歯学 / 生理学 / シグナル伝達 / 唾液腺 / 分泌顆粒 / 耳下腺 / 成熟過程 / エンドサイトーシス / ラツト |
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| Research Abstract |
I hypothesized that rat parotid cell can take amylase from lumen to make secretory granule. I examined that whether parotid gland take color dye into granules by endocytosis, and that whether the dye can be detected in living cells. In this study, I succeeded in detection of fluorescence in immature granules. This result expects visualization of secretory granules. Next, I will examine granule maturation and exocytosis using that method.
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Report
(3 results)
Research Products
(5 results)
