| Project/Area Number |
20791363
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Functional basic dentistry
|
|---|
| Research Institution | Nihon University |
|---|
Principal Investigator |
KATO Osamu Nihon University, 松戸歯学部, 講師 (70349968)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 歯学 / 生理学 / シグナル伝達 / 唾液腺 / 分泌顆粒 / 耳下腺 / 成熟過程 / エンドサイトーシス / ラツト |
|---|
| Research Abstract |
I hypothesized that rat parotid cell can take amylase from lumen to make secretory granule. I examined that whether parotid gland take color dye into granules by endocytosis, and that whether the dye can be detected in living cells. In this study, I succeeded in detection of fluorescence in immature granules. This result expects visualization of secretory granules. Next, I will examine granule maturation and exocytosis using that method.
|
