The research of development of reminral ization activator with long term remaining performance on root dentin surface

• Project/Area Number: 20791379
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Conservative dentistry
• Research Institution: Hokkaido University
• Principal Investigator: OKUYAMA Katsushi Hokkaido University, 大学院・歯学研究科, 助教 (00322818)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 根面象牙質 / 再石灰化 / 根面保持 / pHサイクル / フッ素溶出

Research Abstract

The purpose of this research was to evaluate the fluoride-releasing coating material, which have the performance of long-term remaining on root dentin surface due to caries prevention. The results of this study showed that amount of fluoride release from the coating material was larger than that of current material. Remineralization of root dentin (the measure of caries prevention) by the coating material was indicated more than that of other materials. Fluoride application was made improve bonding strength between dentin and dental material. Then fluoride ion was detected on interface between dentin and dental material.

Research Products

• [Journal Article] Fluorine analysis of human dentin surrounding resin composite after fluoride application by μ-PIGE/PIXE analysis (2011)
  • Author(s): K Okuyama, H Komatsu, 他
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B : Beam Interactions with Materials and Atoms Volume: (印刷中)
  • NAID: 120003596806
  • Peer Reviewed
• [Journal Article] フッ素徐放性レジンの齲蝕抑制効果のpHサイクルによる評価 (2009)
  • Author(s): 木地村太基, 小松久憲, 奥山克史
  • Journal Title: 日本歯科保存学雑誌 52(1) Pages: 39-50
  • NAID: 110007228046
  • Peer Reviewed
• [Journal Article] フッ素徐放性レジンの齲蝕抑制効果のpHサイクルによる評価 (2009)
  • Author(s): 木地村太基、小松久憲、奥山克史, 他
  • Journal Title: 日本歯科保存学雑誌 52巻 Pages: 39-50
  • NAID: 110007228046
  • Peer Reviewed
• [Journal Article] Fluorine analysis of human dentin surrounding resin composite after fluoride application by μ-PIGE/PIXE analysis.
  • Author(s): Okuyama K, Komatsu H, Yamamoto H
  • Journal Title: Nuclear Instruments and Methods in Physics Research Section B : Beam Interactions with Materials and Atoms (in press)
  • NAID: 120003596806
  • Peer Reviewed
• [Presentation] Effect of dentin-remineralization on new root coating material. (2011)
  • Author(s): Okuyama K.
  • Organizer: 89th Meeting of IADR
  • Place of Presentation: San Diego Convention Center, San Diego CA, USA
  • Year and Date: 2011-03-18
• [Presentation] Effect of dentin-remineralization on new root coating material (2011)
  • Author(s): K Okuyama, H Komatsu, 他
  • Organizer: IADR(国際歯科研究学会)
  • Place of Presentation: San Diego Convention Center(サンディエゴ、アメリカ)
  • Year and Date: 2011-03-18
• [Presentation] Fluoride analysis of human enamel around fluoride-containing materials under different pH-cycling by μ-PIGE/PIXER system. (2010)
  • Author(s): Komatsu H, Okuyama K.
  • Organizer: 12th ICNMTA
  • Place of Presentation: The Westin Leipzig, Leipzig, Germany.
  • Year and Date: 2010-07-27
• [Presentation] Fluorine analysis of human dentin around resin composite after fluoride application by μ-PIGE/PIXER system. (2010)
  • Author(s): Okuyama K.
  • Organizer: 12th ICNMTA
  • Place of Presentation: The Westin Leipzig, Leipzig, Germany.
  • Year and Date: 2010-07-27
• [Presentation] Fluorine analysis of human dentin around resin composite after fluoride application by μ-PIGE/PIXER system (2010)
  • Author(s): K Okuyama, H Komatsu, 他
  • Organizer: ICNMTA (International Conference on Nuclear Microprobe Technology and Applications)
  • Place of Presentation: The Westin Leipzig(ライプチヒ、ドイツ)
  • Year and Date: 2010-07-27
• [Presentation] Fluoride analysis of human enamel around fluoride-containing materials under different pH-cycling by μ-PIGE/PIXER system (2010)
  • Author(s): H Komatsu, K Okuyama, 他
  • Organizer: ICNMTA (International Conference on Nuclear Microprobe Technology and Applications)
  • Place of Presentation: The Westin Leipzig(ライプチヒ、ドイツ)
  • Year and Date: 2010-07-27
• [Presentation] フッ素含有材料の乳酸溶液へのフッ素溶出(II) (2010)
  • Author(s): 船戸良基、小島健太郎、奥山克史, 他
  • Organizer: 日本歯科保存学会春期学術大会
  • Place of Presentation: 熊本市民会館(熊本市)
  • Year and Date: 2010-06-04
• [Presentation] フッ素含有材料からの歯質への長期フッ素取り込み量 (2010)
  • Author(s): 小松久憲、船戸良基、奥山克史, 他
  • Organizer: 日本歯科保存学会春期学術大会
  • Place of Presentation: 熊本市民会館(熊本市)
  • Year and Date: 2010-06-04
• [Presentation] 充填1年後におけるフッ素含有材料の齲蝕抑制効果 (2010)
  • Author(s): 小松久憲、小松久憲、奥山克史, 他
  • Organizer: 日本歯科保存学会春期学術大会
  • Place of Presentation: 熊本市民会館(熊本市)
  • Year and Date: 2010-06-04
• [Presentation] Effect of caries inhibition on new root coating material. (2010)
  • Author(s): Okuyama K.
  • Organizer: 38rd Meeting of AADR
  • Place of Presentation: Walter E. Washington Convention Center, Washington DC, USA
  • Year and Date: 2010-03-14
• [Presentation] Effect of caries inhibition on new root coating material (2010)
  • Author(s): 奥山克史, 小松久憲, 他
  • Organizer: AADR(アメリカ歯科研究学会)
  • Place of Presentation: Walter E.Washington Convention Center(ワシントンDC)
  • Year and Date: 2010-03-04
• [Presentation] 核反応による歯質中のフッ素分布測定(VIII) (2009)
  • Author(s): 小松久憲、奥山克史
  • Organizer: 第4回高崎量子応用研究シンポジウム
  • Place of Presentation: 高崎市高崎シティーギャラリー
  • Year and Date: 2009-10-08
• [Presentation] 核反応による齲蝕歯中のフッ素濃度分布の測定 (2009)
  • Author(s): 小松久憲, 山本洋子, 奥山克史, 他
  • Organizer: 日本歯科保存学会春期学術大会
  • Place of Presentation: 札幌コンベンションセンター(札幌市)
  • Year and Date: 2009-06-11
• [Presentation] フッ素含有材料の乳酸溶液へのフッ素溶出 (2009)
  • Author(s): 小島健太郎、小松久憲、奥山克史, 他
  • Organizer: 日本歯科保存学会春期学術大会
  • Place of Presentation: 札幌コンベンションセンター(札幌市)
  • Year and Date: 2009-06-11
• [Presentation] フッ素含有材料の乳酸溶液へのフッ素溶出(II) (2009)
  • Author(s): 船戸良基、奥山克史
  • Organizer: 日本歯科保存学会春期学会(第132回)
  • Place of Presentation: 熊本市熊本市民会館
  • Year and Date: 2009-06-04
• [Presentation] フッ素含有材料からの歯質への長期フッ素取り込み量 (2009)
  • Author(s): 小松久憲、奥山克史
  • Organizer: 日本歯科保存学会春期学会(第132回)
  • Place of Presentation: 熊本市熊本市民会館
  • Year and Date: 2009-06-04
• [Presentation] 充填1年後におけるフッ素含有材料の齲蝕抑制効果 (2009)
  • Author(s): 小島健太郎、奥山克史
  • Organizer: 日本歯科保存学会春期学会(第132回)
  • Place of Presentation: 熊本市熊本市民会館
  • Year and Date: 2009-06-04