Development of periodontal regenerative materials using mesenchymal stem cells in human wisdom tooth germs

• Project/Area Number: 20791380
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Conservative dentistry
• Research Institution: Tohoku University
• Principal Investigator: NISHIHARA Daisuke Tohoku University, 大学院・歯学研究科, 大学院非常勤講師 (10431587)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: ティッシュエンジニアリング / 生体材料 / 歯根膜再生 / 幹細胞 / スキャフォルド / ティシュエンジニアリング / 幹組胞

Research Abstract

Mesenchymal stem cells have the possibility useful for the stem cell treatment and the tissue engineering. In this research, we examined characteristic of mesenchymal stem cells in human wisdom tooth germs. As a result, human wisdom tooth germs are useful for the stem cell treatment and the tissue engineering.

Research Products

• [Journal Article] Isolation and comparison of mesenchymal stem cells derived from human wisdom tooth germs and periodontal ligament in vitro (2010)
  • Author(s): D.Nishihara, et al
  • Journal Title: Interface Oral Health Science 2009 Pages: 55-56
  • Peer Reviewed
• [Journal Article] Isolation and comparison of mesenchymal stem cells derived from human wisdom tooth germs and periodontal ligament in vitro (2010)
  • Author(s): D.Nishihara, et al
  • Journal Title: Interface Oral Health Science (未定, 印刷中)
• [Presentation] The Influence of Mesenchymal Stem Cells Growth Medium for Isolation of STRO-1 Positive Cells from Human Periodontal Ligament (2011)
  • Author(s): N.Endo, D.Nishihara, et al
  • Organizer: Interface Oral Health Science in Sendai
  • Place of Presentation: 仙台
  • Year and Date: 2011-03-08
• [Presentation] Characterization of STRO-1 positive cells derived from Human Wisdom Tooth Germs. (2011)
  • Author(s): Y.Iwamatsu-Kobayashi, D.Nishihara, et al
  • Organizer: Interface Oral Health Science in Sendai
  • Place of Presentation: 仙台
  • Year and Date: 2011-03-08
• [Presentation] Characterization of STRO-1 positive cells derived from Human Wisdom Tooth Germs (2011)
  • Author(s): Y.Iwamatsu-Kobayashi, D.Nishihara, et al
  • Organizer: インターフェイス口腔健康科学国際シンポジウム
  • Place of Presentation: 仙台
  • Year and Date: 2011-03-08
• [Presentation] The Influence of Mesenchymal Stem Cells Growth Medium for Isolation of STRO-1 Positive Cells from Human Periodontal Ligament (2011)
  • Author(s): N.Endo, D.Nishihara, et al
  • Organizer: インターフェイス口腔健康科学国際シンポジウム
  • Place of Presentation: 仙台
  • Year and Date: 2011-03-08
• [Presentation] Isolation and comparison of mesenchymal stem cells derived from huma n wisdom toothgerms and periodontal ligament in vitro (2009)
  • Author(s): D. Nishihara, et.al.
  • Organizer: Interface Oral Health Science in Sendai
  • Place of Presentation: 仙台市
  • Year and Date: 2009-01-16
• [Presentation] Isolation and comparison of mesenchymal stem cells derived from human wisdom tooth germs and periodontal ligament in vitro. (2009)
  • Author(s): D.Nishihara, M.Hirata, et al
  • Organizer: Interface Oral Health Science in Sendai
  • Place of Presentation: 仙台
  • Year and Date: 2009-01-15
• [Book] Isolation and comparison of mesenchymal stem cells derived from human wisdom tooth germs and periodontal ligament in vitro(Interface Oral Health Sciencex) (2009)
  • Author(s): D.Nishihara, et al
  • Publisher: springer