| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
The aim of this study was to evaluate the biological specificity in the wide pH environment of infected root canal-related bacteria : Enterococcus faecalis and Bifidobacterium longum and caries-related bacteria : Bifidobacterium dentium.E. faecalis grew well at wide pH range of arginine- containing complex medium, suggesting that this bacteria can grow using amino acid such as arginine in the exudates of persistent infected root canals where calcium hydroxide medicaments are ineffective or poor carbohydrate supply. Meanwhile, the high survival rate and intracellular pH maintenance ability of bifidobacteria comparable to Streptococcus mutans in the acidic environment may account for why bifidobacteria exist as stable species in acidic caries lesions together with mutans streptococci.
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