Pathohistological study of the healing process in the rat root apical area using bioactive glass after apicoectomy

• Project/Area Number: 20791410
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Conservative dentistry
• Research Institution: Fukuoka Dental College
• Principal Investigator: EIDA Taro Fukuoka Dental College, 歯学部, 助教 (60425246)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 生体活性ガラス / 骨補填材 / 歯根端切除術

Research Abstract

In this study, after apicoectomy of the rat maxillary first molar mesial tooth roots, BAG granules with the mean diameter of 20μm or 45μm were filled in the apicoectomy area. It has been suggested that BAG, especially, B-BAG with a slightly large particle size, is a useful biomaterial with high bone conductivity in the apicoectomy.

Research Products

• [Journal Article] Expression of TGF-β1 during the healing process of rat periapical lesions. (2008)
  • Author(s): Hisashi Anan, Hiroshi Matsura, Masahiro Yoneda, Shigeki Matsuya, Toshio Izumi, Kazuhiko Yamada, Takao Hirofuji, Noriyoshi Matsumoto, Taro Eida, Akie Fukushima, Chieko Shigeyama
  • Journal Title: J Fukuoka Dent Coll 34 Pages: 133-146
  • NAID: 110007008225
• [Presentation] 口腔乾燥症患者における唾液中コルチゾルおよびクロモグラニンAの評価 (2009)
  • Author(s): 茂山千英子(榮田太郎)
  • Organizer: 日本歯科保存学会
  • Place of Presentation: 仙台国際センター
  • Year and Date: 2009-10-09
• [Presentation] ヒト歯根膜細胞における炎症性サイトカインによるSOCSの発現
  • Author(s): 福島晶絵、加治屋浩、泉利雄、片山知子、茂山千英子、榮田太郎、松本典祥、岡部幸司、阿南壽
  • Organizer: 第35回福岡歯科大学学会学術大会
  • Place of Presentation: 福岡
• [Presentation] 口腔乾燥症患者における唾液中コルチゾルおよびクロモグラニンAの評価
  • Author(s): 茂山千英子、泉利雄、松本典祥、榮田太郎、小松晶絵、國本利雄、久原裕子、阿南壽
  • Organizer: 第131回日本歯科保存学会
  • Place of Presentation: 仙台