Efficacy of polysaccharide polymers as sustained-release carrier
Project/Area Number |
20791455
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Prosthetic dentistry
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Research Institution | Osaka Dental University |
Principal Investigator |
KAWAMOTO Akiyo Osaka Dental University, 歯学科, 助教 (50368156)
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Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 歯科補綴学一般 / ヒアルロン酸 / 骨芽細胞 / 高分子多糖 / 骨粗鬆症 |
Research Abstract |
The purpose of this study was to examine the efficacy of polysaccharide polymers as a sustained-release carrier for recovery and regeneration of periodontal tissue in vitro. Osteoblast-like cells were cultured with hyaluronan for examining the osteoblast activity, cell attachment, proliferation and migration with or without anti-CD44mAb. Effect of HA on osteoblast activity, cell attachment and proliferation was related to CD44 but cell migration was not.
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] Influence of adipocytokines on differentiation of pro-osteoblastic cells.2008
Author(s)
A Kamada, T Ikeo, Y Yoshikawa, E Domae, S Goda, I Tamura, H Kon-I, J Okazaki, A Kawamoto, Y Komasa, I Toda, F Suwa.
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Journal Title
J Oral Tissue Engin. 6(1)
Pages: 17-23
NAID
Related Report
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[Presentation] Heparan sulfate proteoglycans modulate osteogenic differentiation through heparan sulfate chains.2009
Author(s)
A Kamada, T Ikeo, Y Yoshikawa, E Domae, S Goda, I Tamura, A Kawamoto, J Okazaki, Y Komasa, Y Takaishi, T Miki, T Fujita.
Organizer
The 30th Annual Meeting of the American Society for Bone and Mineral Research.
Place of Presentation
Montreal
Year and Date
2009-09-15
Related Report
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[Presentation] Various roles of syndecan family in osteoblastic cells.2009
Author(s)
T Ikeo, A Kamada, Y Yoshikawa, E Domae, S Goda, I Tamura, A Kawamoto, J Okazaki, Y Komasa, Y Takaishi, T Miki, T Fujita.
Organizer
The 30th Annual Meeting of the American Society for Bone and Mineral Research.
Place of Presentation
Montreal
Year and Date
2009-09-13
Related Report
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[Presentation] Adipocytokine influences differentiation of osteoblasts.2008
Author(s)
A Kamada, T Ikeo, Y Yoshikawa, E Domae, S Goda, I Tamura, A Kawamoto, J Okazaki, Y Komasa, I Toda, F Suwa.
Organizer
The 4th Sino-Japanese Conference on Stomatology 2008.
Place of Presentation
西安
Year and Date
2008-09-29
Related Report
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