Project/Area Number |
20791458
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Dental engineering/Regenerative dentistry
|
Research Institution | Tohoku University |
Principal Investigator |
TAKAHASHI Masatoshi Tohoku University, 大学院・歯学研究科, 助教 (50400255)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
|
Keywords | チタン合金 / 歯科用合金 / 抗菌性 / 生体適合性 / 耐食性 / 歯科修復物 / 歯科補綴物 / チタン銀合金 |
Research Abstract |
Aiming to develop dental titanium alloys with antibacterial property and biocompatibility, we prepared experimental Ti-Ag alloys and investigated their properties. The Ti-Ag alloys inhibited biofilm formation, but did not have bactericidal activity. Calcium phosphates were spontaneously formed on the Ti-Ag alloys in a simulated body fluid. The Ti-Ag alloys had excellent corrosion resistance similar to that of titanium. It was suggested that the Ti-Ag alloys were a new type of biomaterial which inhibited biofilm formation without affecting normal microbial flora.
|