Development of functional titanium implant for bone attachment

• Project/Area Number: 20791467
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Hiroshima University
• Principal Investigator: HIRATA Isao Hiroshima University, 大学院・医歯薬学総合研究科, 助教 (40346507)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: チタン / アルキルホスホン酸 / 表面改質 / 表面プラズモン / 生体適合性 / バイオミネラリゼーション / 組織接着 / 骨再生 / 表面因子

Research Abstract

This study, based on surface treatment and analysis technology acquired from the applicant, used alkalyphosphonic acids and biomineralization peptide onto titanium substrates and then established a method of reforming the surface of titanium implant bone adhesion. These immobilization techniques can be expected to improve significantly the ability of the titanium implant bone regeneration and tissue adhesive.