Elucidation of the role of serotonin and serotonin receptors in neuropathic pain in inferior alveolar nerve.

Research Project

Project/Area Number	20791502
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Surgical dentistry
Research Institution	Niigata University
Principal Investigator	TSURUMAKI Tatsuru Niigata University, 医歯学系, 助教 (10345522)
Project Period (FY)	2008 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000) Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	神経因性疼痛 / セロトニン / 下歯槽神経 / セロトニン受容体
Research Abstract	I created an experimental animal model of neuropathic pain on the inferior alveolar nerve by using a modified method of the neuropathy model created by Yonehara et al. 5-HT1B, 1F, 2A mRNAs were detected by RT-PCR in rat inferior alveolar nerve. However, expressions of serotonin receptors mRNAs were not shown significant change.

Report

(4 results)