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Elucidation of the role of serotonin and serotonin receptors in neuropathic pain in inferior alveolar nerve.

Research Project

Project/Area Number 20791502
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionNiigata University

Principal Investigator

TSURUMAKI Tatsuru  Niigata University, 医歯学系, 助教 (10345522)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords神経因性疼痛 / セロトニン / 下歯槽神経 / セロトニン受容体
Research Abstract

I created an experimental animal model of neuropathic pain on the inferior alveolar nerve by using a modified method of the neuropathy model created by Yonehara et al. 5-HT1B, 1F, 2A mRNAs were detected by RT-PCR in rat inferior alveolar nerve. However, expressions of serotonin receptors mRNAs were not shown significant change.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (4 results)

All 2010 2008 Other

All Presentation (3 results) Remarks (1 results)

  • [Presentation] ラット下歯槽神経におけるセロトニン受容体サブタイプmRNA発現の検討2010

    • Author(s)
      弦巻立
    • Organizer
      日本歯科麻酔学会学術集会
    • Place of Presentation
      横須賀芸術劇場、産業交流プラザ(神奈川)
    • Year and Date
      2010-10-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] ラット下歯槽神経におけるセロトニン受容体サブタイプmRNA発現の検討2010

    • Author(s)
      弦巻立, 他2名
    • Organizer
      第38回日本歯科麻酔学会学術集会
    • Related Report
      2010 Final Research Report
  • [Presentation] 口腔外科手術患者の術後疼痛と心理的因子の関連性の検討2008

    • Author(s)
      田中裕、弦巻立、染矢源治, 他
    • Organizer
      日本歯科麻酔学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-10-09
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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