Expression analysis of the S100A7 protein in the oral squamous cell carcinoma and oral precancer disease.

• Project/Area Number: 20791563
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: Fukuoka Dental College
• Principal Investigator: FUKUZAWA Hideaki Fukuoka Dental College, 歯学部, 助教 (90465724)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 口腔外科学一般 / 歯学 / 癌 / 細胞・組織

Research Abstract

In the current study,using tissue samples are diagnosed with oral leukoplakia and squamous cell carcinoma primarily treated at our department, using a mouse monoclonal S100A7 antibody, performed immunohistochemical staining.As a result, many cases of variations in expression of both leukoplakia and oral squamous cell carcinoma. Not the result of what was expected, it was considered necessary will be considered along with other oral precancerous lesions and number of additional samples.