| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
In this study, we focus on endocannainoid (anandamide(AEA), 2-AG) for an indicator of estimation of the relationship between Arteriosclerotic disease and Periodontal disease. We investigated the relationship between periodontal progression and AEA and 2-AG in periodontal pocket and total cholesterol, triglyceride, AEA and 2-AG inperipheral blood. None of significant relationship observed between periodontal progression and all of them.But they tend to increase proportionally with periodontal disease progression, especially in patient with heart disease. These results suggested that endocannabinoid are produced in periodontal pocket and these cannaibnoid affect systemic metabolism via blood flow.
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