Elucidation of relationship of periodontitis and antioxidant property with saliva, and construction of a novel evaluation of periodontal disease index.

• Project/Area Number: 20791622
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Periodontal dentistry
• Research Institution: Kanagawa Dental College
• Principal Investigator: YOSHINO Fumihiko Kanagawa Dental College, 生体管理医学講座薬理学分野, 講師 (20308307)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 活性酸素 / 唾液 / 歯周疾患 / 抗酸化 / 電子スピン共鳴 / 診断 / 活性酸素種

Research Abstract

The periodontal pathogenic bacteria infection was found to increase in reactive oxygen species (O2^<・->) scavenging ability of saliva. This phenomenon has been suggested that induced to maintain homeostasis of the oral environment. In addition, O2^<・->scavenging for the measurement was considered that it is possible to establish a novel prognostic indicator and an objective diagnosis of periodontal disease in the near future.

Research Products

• [Journal Article] 電子スピン共鳴法(ESR)を用いた魚肉ペプチド(FPP)の抗酸化能評価-第3報- (2009)
  • Author(s): 吉野文彦、小林杏、前畑洋次郎、万建栄、本多和紀、鈴木博昌、李昌一
  • Journal Title: AOB研究会プロシーディング Pages: 6-8
• [Journal Article] 電子スピン共鳴法(ESR)を用いた魚肉ペプチド(FPP)の抗酸化能評価-第3報- (2009)
  • Author(s): 吉野文彦、小林杏、前畑洋次郎、万建栄、本多和紀、鈴木博昌、李昌一
  • Journal Title: AOB研究会プロシーディング 8巻 Pages: 6-8
• [Presentation] 歯科衛生士のためのアンチエイジング講座 (2009)
  • Author(s): 吉野文彦
  • Organizer: よこすかデンタルフェア'09
  • Place of Presentation: 横須賀口腔衛生センター
  • Year and Date: 2009-10-04
• [Presentation] 歯科衛生士のためのア,チエイジング講座 (2009)
  • Author(s): 吉野文彦
  • Organizer: よこすかデンタルフェア'09
  • Place of Presentation: 横須賀市
  • Year and Date: 2009-10-04
• [Presentation] Assessment of antioxidant property of peptide from boiled fish paste (2009)
  • Author(s): Yoshino F., Maehata Y., Kobayashi K., Yoshida A., Sugiyama S., Honda K., Suzuki H., Lee M-C
  • Organizer: International Association for Dental Research
  • Place of Presentation: Miami, Florida, USA
  • Year and Date: 2009-04-03
• [Presentation] アンチエイジング外来での検査と指導 (2009)
  • Author(s): 吉野文彦
  • Organizer: 日本抗加齢歯科医学研究会
  • Place of Presentation: 鶴見大学会館
  • Year and Date: 2009-03-29