Profiling the cytokines in gingival crevicular fluid of postmenopausal woman.

• Project/Area Number: 20791626
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Periodontal dentistry
• Research Institution: Aichi Gakuin University
• Principal Investigator: YAMAMOTO Genta Aichi Gakuin University, 歯学部, 講師 (30421241)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 歯周病 / 骨粗鬆症 / エストロゲン / 閉経後女性 / 炎症性サイトカイン / ビスフォスフォネート製剤 / Periodontal Medicine

Research Abstract

Increased IL-1 and TNF-α levels in post-menopausal woman group suggests that reduced estrogen at menopause does correlate with increased inflamation cytokines in GCF.

Research Products

• [Journal Article] 閉経後女性の歯周病と骨粗鬆症所見の関係および骨密度評価継続者の歯周病所見の変化. (2009)
  • Author(s): 坂野雅洋, 稲垣幸司, 山本弦太, 野田貴弘, 野口俊英, 森田一三, 中垣晴男, 井澤浩之, 蜂谷裕道, 細井延行, 三木隆己
  • Journal Title: Osteoporosis Jpn 17(3) Pages: 563-569