| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
The hydrogen sulfide(H_2S) is the main source of oral malodor. The production activity and the production mechanism of H_2S by the oral indigenous bacteria, Veillonella species and Actinomyces species, were examined. It was shown that these bacterial species have H_2S production activity and the activity was influenced by the environmental factors such as pH and the lactate concentration. Moreover, the mechanisms were slightly different depending on the bacterial strain even within same belonging. There has actually been suggested that there is possibility of H_2S production activity being influenced by its coexistence with other saccharolytic bacteria, therefore it is necessary to understand the cause of oral malodor in relation to bacteria not only as a single bacteria but also as the entire oral cavity including the oral biofilm microorganism and the oral environmental factors.
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