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The development of genetic tests regarding cariogenicity of mutans streptococci

Research Project

Project/Area Number 20791635
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Social dentistry
Research InstitutionNiigata University

Principal Investigator

KANEKO Noboru  Niigata University, 医歯学系, 助教 (00397126)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords歯学 / ミュータンスレンサ球菌 / 齲蝕原性
Research Abstract

An important virulence factor of S. mutans is a glucosyltransferase synthesizing water-insoluble glucan (WIG) from sucrose. We performed sequencing of the gtfB gene of 72 S. mutans isolates derived from primary school students.
GtfB coded by gtfB gene possess two functional domain. The carboxyl-terminal portion of GtfB is called the glucan binding domain and is coded by the direct repeating units. The results of this study indicated that the number of the repeating sequences in gtfB is associated with WIG synthesis by S.mutans

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (11 results)

All 2010 2009 2008

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (7 results)

  • [Journal Article] Availability of air powder polishing with crystalline cellulose as a prophylactic method for orthodontic patients with a multi-bracket appliance.2010

    • Author(s)
      Shinzawa-Fukushima M, Kanaya T,Kaneko N, Morita S, Miyazaki H, SaitoI
    • Journal Title

      Orthodontic Waves 69

      Pages: 75-81

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 乳・幼児健診に併設し実施する間接健診および個別指導が行動変容に及ぼす影響2010

    • Author(s)
      葭原明弘, 金子昇, 杉本智子, 清田義和, 佐藤徹, 宮崎秀夫
    • Journal Title

      口腔衛生学会雑誌 60(1)

      Pages: 11-16

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Availability of air powder polishing with crystalline cellulose as a prophylactic method for orthodontic patients with a multi-bracket appliance2010

    • Author(s)
      Shinzawa-Fukushima M, Kanaya T, Kaneko N, Morita S, Miyazaki H, Saito I
    • Journal Title

      Orthodontic Waves

      Volume: 69(2) Pages: 75-81

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Availability of air powder polishing with crystalline cellulose as a prophylactic method for orthodontic patients with a multi-bracket appliance2010

    • Author(s)
      Fukushima M, Kanaya T, Kaneko N, Morita S, Miyazaki H, Saito I
    • Journal Title

      Orthodontic Waves (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Glucan synthesis by Streptococcus mutans and caries incidence in schoolchildren.2010

    • Author(s)
      Kaneko N, Umetsu H, Yoshihara A,Sakuma S, Hanada N, Miyazaki H
    • Organizer
      88th General Session of the IADR
    • Place of Presentation
      Barcelona(Spain)
    • Related Report
      2010 Final Research Report
  • [Presentation] Glucan synthesis by Streptococcus mutans and caries incidence in schoolchildren2010

    • Author(s)
      Kaneko N, Umetsu H, Yoshihara A, Sakuma S, Hanada N, Miyazaki H
    • Organizer
      88th General Session of the IADR
    • Place of Presentation
      Barcelona (Spain)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Relationship between salivary Porphyromonas gingivalis and periodontal conditions.2009

    • Author(s)
      Naito H, Takayama K, Masuda H,Tachino A, Ishihara Y, Kaneko N, Miyazaki H
    • Organizer
      87th General Session of the IADR
    • Place of Presentation
      Miami(USA)
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清および唾液中Porphyromonas gingivalis 抗体価と冠動脈性心疾患リスク因子との関連性の検討2009

    • Author(s)
      金子昇, 濃野要, 今井奨, 葭原明弘, 花田信弘, 宮崎秀夫
    • Organizer
      口腔衛生会誌, 59(4):496
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清および唾液中抗Porphyromonas gingivalis 抗体価と冠動脈性心疾患のリスク因子との関連2009

    • Author(s)
      金子昇, 花田信弘
    • Organizer
      日本細菌学雑誌, 64(1):163
    • Related Report
      2010 Final Research Report
  • [Presentation] フッ化物洗口実施児童におけるStreptococcus mutansの非水溶性グルカン合成能とう蝕との関連2008

    • Author(s)
      梅津英裕, 金子昇, 葭原明弘, 佐久間汐子, 宮崎秀夫
    • Organizer
      平成20年度新潟歯学会第1回例会
    • Place of Presentation
      新潟市
    • Year and Date
      2008-07-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] フッ化物洗口実施児童におけるStreptococcus mutans の非水溶性グルカン合成能とう蝕との関係2008

    • Author(s)
      梅津英裕, 金子昇, 葭原明弘, 佐久間汐子, 宮崎秀夫
    • Organizer
      新潟歯学会雑誌, 38(2):131-132
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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