Development of Maternal and Neonatal Health Care Systems for the Prevention of Neonatal Early-Onset Group B Streptococcal Disease from the Viewpoint of Medical Cooperation
| Project/Area Number |
20791749
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | Aichi Medical University |
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Principal Investigator |
WAKIMOTO Hiroko Aichi Medical University, 看護学部, 准教授 (40336706)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 母子感染 / 母子感染予防 / GBS / 新生児 / 新生児搬送 / 薬剤感受性 / 血清型 / 看護学 / 感染症 / 細菌 |
|---|
| Research Abstract |
[Study 1] I compared microbiological screening methods during pregnancy between mothers (group A) whose neonates developed early onset group B streptococcal disease (EOGBSD) and mothers with GBS colonization (group B) whose neonates did not. There were a significantly higher proportion of pregnant women screened before 35 gestational weeks in group A than in group B. Among EOGBSD neonates who required neonatal transport, the interval between disease onset and admission was significantly longer in neonates whose onset occurred at midnight than those at period with onset other than midnight. [Study 2] Next, I examined microbiological characteristics of invasive isolates from EOGBSD the neonates (n=14) and colonized isolates from the neonatal pharynx (n=61) and from the genital tract of pregnant women (n=247). There were no significant differences in the susceptibility of antimicrobial agents between invasive and colonized isolates. In conclusion, implementation of universal obstetric screening and development of neonatal transport systems may improve the prognosis of EOGBSD.
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Report
(4 results)
Research Products
(12 results)
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[Journal Article] 新生児および妊婦褥婦由来B群レンサ球菌の薬剤感受性と血清型-多施設共同研究1999年～2009年-2011
Author(s)
脇本寛子, 脇本幸夫, 矢野久子, 松原康策, 宮川創平, 吉田敦, 奥住捷子, 佐藤洋子, 澤田恭子, 山田恭聖, 二村真秀 , 北川眞理子, 佐藤剛, 南正明, 長谷川忠男
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Journal Title
日本感染症学雑誌 85(2)
Pages: 155-160
NAID
Related Report
Peer Reviewed
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[Journal Article] 新生児および妊婦褥婦由来B群レンサ 球菌の薬剤感受性と血清型-多施設共同研究1999年～2009年-2011
Author(s)
脇本寛子, 脇本幸夫, 矢野久子, 松原康策, 宮川創平, 吉田敦, 奥住捷子, 佐藤洋子, 澤田恭子, 山田恭聖, 二村真秀, 北川眞理子, 佐藤剛, 南正明, 長谷川忠男
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Journal Title
日本感染症学雑誌
Volume: 85
Pages: 155-160
NAID
Related Report
Peer Reviewed
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[Journal Article] 新生児搬送を必要とした早発型B群溶連菌感染症症例 臨床的特徴と搬送の問題点の検討2009
Author(s)
脇本寛子, 矢野久子, 松原康策, 宮川創平, 山田恭聖, 二村真秀, 相澤まどか, 永山義久, 濱口賢子, 由良和夫, 加藤文英, 土井まつ子, 都もと子, 保科清, 佐藤剛, 鈴木悟, 戸苅創
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Journal Title
日本周産期・新生児学会雑誌 45(4)
Pages: 1398-1403
NAID
Related Report
Peer Reviewed
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[Journal Article] 新生児搬送を必要とした早発型B群溶連菌感染症症例 臨床的特徴と搬送の問題点の検討2009
Author(s)
脇本寛子, 矢野久子, 松原康策, 宮川創平, 山田恭聖, 二村真秀, 相澤まどか, 永山善久, 濱口賢子, 由良和夫, 加藤文英, 土井まつ子, 都もと子, 保科清, 佐藤剛, 鈴木悟, 戸苅創
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Journal Title
日本周産期・新生児医学会雑誌 45
Pages: 1398-1403
NAID
Related Report
Peer Reviewed
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[Presentation] 新生児血液髄液由来GBS株とGBS保菌新生児・妊婦由来の血清型別と薬剤感受性の推移2010
Author(s)
脇本寛子, 脇本幸夫, 矢野久子, 宮川創平, 吉田敦, 奥住捷子, 佐藤洋子 , 相澤まどか, 山田恭聖, 二村真秀, 戸苅創
Organizer
第42回レンサ球菌感染症研究会
Place of Presentation
東京
Year and Date
2010-06-26
Related Report
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[Presentation] 新生児GBS感染症敗血症/髄膜炎発症株と非発症株における型別法と薬剤感受性試験の比較検討2008
Author(s)
脇本寛子, 脇本幸夫, 矢野久子, 三澤慶樹, 吉田敦, 奥住捷子, 鈴木悟, 戸苅創, 相澤まどか, 佐藤洋子, 澤田恭子, 土井まつ子, 宮川創平, 溝上雅史
Organizer
第41回レンサ球菌感染症研究会
Place of Presentation
東京
Year and Date
2008-06-21
Related Report
