The monitoring of working memory in the rat prefrontal cortex

• Project/Area Number: 20830012
• Research Category: Grant-in-Aid for Young Scientists (Start-up)
• Allocation Type: Single-year Grants
• Research Field: Experimental psychology
• Research Institution: University of Tsukuba
• Principal Investigator: HAYASHI Kazuko University of Tsukuba, 医学部, 研究員 (70512995)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,341,000 (Direct Cost: ¥2,570,000、Indirect Cost: ¥771,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥1,781,000 (Direct Cost: ¥1,370,000、Indirect Cost: ¥411,000)
• Keywords: ラット / 前頭前野 / ワーキングメモリー

Research Abstract

In primates, the prefrontal cortex is critically involved in higher cognitive functions such as working memory, temporal organization of behavior, and decision making. Working memory is defined as the ability to hold information to guide prospective behavior. We investigated roles of the rat prefrontal cortex in the monitoring of working memory to evaluate executive function in rodents.

Research Products

• [Presentation] Effects of NMDA and AMPA receptor blockade in the ventral hippocampus on spatial working memory in rats (2009)
  • Author(s): Hayashi, K., Ichitani, Y
  • Organizer: Society for Neuroscience 39th
  • Place of Presentation: Chicago
  • Year and Date: 2009-10-21
• [Presentation] Effects of NMDA and AMPA receptor blockade in the ventral hippocampus on spatial working memory in rats (2009)
  • Author(s): 林和子・一谷幸男
  • Organizer: Society for Neuroscience 39th
  • Place of Presentation: Chicago(USA)
  • Year and Date: 2009-10-21
• [Presentation] ラットの放射状迷路課題習得に及ぼす内側前頭前野D1受容体遮断の効果 (2009)
  • Author(s): 林和子・一谷幸男
  • Organizer: 日本動物心理学会第69回大会
  • Place of Presentation: 岐阜大学
  • Year and Date: 2009-09-26
• [Presentation] ラットの放射状迷路課題習得に及ぼす内側前頭前野D1受容体遮断の効果 (2009)
  • Author(s): 林和子・一谷幸男
  • Organizer: 日本動物心理学会第69回大会
  • Place of Presentation: 岐阜大学(岐阜県)
  • Year and Date: 2009-09-26
• [Presentation] Roles of NMDA and AMPA receptors in the rat ventral hippocampus in spatial working memory (2009)
  • Author(s): Hayashi, K., Ichitani, Y
  • Organizer: 第32回日本神経科学大会
  • Place of Presentation: 名古屋国際会議場
  • Year and Date: 2009-09-17
• [Presentation] Roles of NMDA and AMPA receptors in the rat ventral hippocampus in spatial working memory (2009)
  • Author(s): 林和子・一谷幸男
  • Organizer: 第32回日本神経科学大会
  • Place of Presentation: 名古屋国際会議場(愛知県)
  • Year and Date: 2009-09-17
• [Presentation] Differential effects of NMDA receptor blockade in the prefrontal cortex and hippocampus on spatial working memory in rats (2009)
  • Author(s): Hayashi, K., Yoshihara, T., Ichitani, Y
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto
  • Year and Date: 2009-07-28
• [Presentation] Differential effects of NMDA receptor blockade in the prefrontal cortex and hippocampus on spatial working memory in rats (2009)
  • Author(s): Hayashi, K., Yoshihara, T., Ichitani, Y.
  • Organizer: The 36th Congress of the International Union of Physiological Sciences
  • Place of Presentation: Kyoto(Japan)
  • Year and Date: 2009-07-28
• [Presentation] ラットの遅延挿入放射状迷路課題遂行に及ぼす内側前頭前野6-OHDA損傷の効果 (2008)
  • Author(s): 林和子・中原大一郎・一谷幸男
  • Organizer: 日本動物心理学会第68回大会
  • Place of Presentation: 常磐大学
  • Year and Date: 2008-09-13
• [Presentation] ラットの遅延挿入放射状迷路課題遂行に及ぼす内側前頭前野6-OHDA損傷の効果 (2008)
  • Author(s): 林和子・中原大一郎・一谷幸男
  • Organizer: 日本動物心理学会(第68回大会)
  • Place of Presentation: 常磐大学
  • Year and Date: 2008-09-13
• [Remarks] 林和子,ラットの空間的作業記憶におけるグルタミン酸受容体の役割,第126回海馬研究会,2009/12/19,同志社大学