| Project/Area Number |
20840027
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Kyoto University |
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Principal Investigator |
SAKAUE Takahiro Kyoto University, 理学研究院, 助教 (30512959)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥2,951,000 (Direct Cost: ¥2,270,000、Indirect Cost: ¥681,000)
Fiscal Year 2009: ¥1,352,000 (Direct Cost: ¥1,040,000、Indirect Cost: ¥312,000)
Fiscal Year 2008: ¥1,599,000 (Direct Cost: ¥1,230,000、Indirect Cost: ¥369,000)
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| Keywords | DNA / 高分子物理学 / 非平衡ダイナミクス / トポロジー / 高分子鎖 / 一分子実験 / 折り畳み / 生体高分子 / translocation / 微小空間 / 細胞モデル / 核モデル / 折り畳み転移 / ソフトマター / ダイナミクス / 非平衡 / 生物物理 |
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| Research Abstract |
Motivated by the recent progress in the single molecule experiments, we have theoretically studied the behaviors of single (bio) polymers from various viewpoints. Examples include (i) the folding transition of giant DNA molecules, (ii) the decompression and escape dynamics of polymers and (iii) the topological effect in circular DNAs, etc. In addition to the fundamental material properties, we have also discussed their biological implications as well.
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