Dielectrophoresis-based cell patterning for cell culture chip
| Project/Area Number |
20860017
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Tohoku University |
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Principal Investigator |
INO Kosuke Tohoku University, 大学院・環境科学研究科, 助教 (00509739)
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| Co-Investigator(Renkei-kenkyūsha) |
MATSUE Tomokazu 東北大学, 大学院・環境科学研究科, 教授 (70173797)
SHIKU Hitoshi 東北大学, 大学院・環境科学研究科, 准教授 (10361164)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,289,000 (Direct Cost: ¥2,530,000、Indirect Cost: ¥759,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,729,000 (Direct Cost: ¥1,330,000、Indirect Cost: ¥399,000)
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| Keywords | 誘電泳動 / 細胞パターニング / 細胞チップ / バイオMEMS / negative dielectrophoresis / manipulation of microparticles / array patterns of microparticles / multilayered electrodes |
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| Research Abstract |
In this study, dielectrophoresis-based cell patterning was developed for cell culture chip. Electrodes were designed and electric field simulations were performed to manipulate bioparticles toward target areas. Based on the simulation results, several kinds of devices were fabricated for the formation of localized and non-uniform electric fields. When an appropriate AC voltage was applied to the electrode, array patterns of microparticles such as polystyrene beads, yeasts and cells were rapidly fabricated on the target substrate with ease. The results suggest that the devices can be widely applied for tissue engineering and drug screening.
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Report
(3 results)
Research Products
(14 results)
