Study of telomere clustering in fission yeast

• Project/Area Number: 20870003
• Research Category: Grant-in-Aid for Young Scientists (Start-up)
• Allocation Type: Single-year Grants
• Research Field: Genetics/Genome dynamics
• Research Institution: University of Tsukuba
• Principal Investigator: SUGIYAMA Rie University of Tsukuba, 大学院・生命環境科学研究科, 研究員 (10503899)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
• Keywords: 分裂酵母 / テロメア

Research Abstract

It has been reported that meiotic telomere clustering, conserved from yeast to human, is important for meiotic chromosome recombination and segregation. In addition, telomere clustering is observed during mitosis in fission yeast. However, the detailed mechanism remains unclear. Genetic screening was performed to identify new factors involved in telomere clustering, and several candidate clones were obtained in this screening.