Molecular mechanisms of transcriptional coactivator which has putative binding activity with methylcytosine during learnin
| Project/Area Number |
20870037
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
HATAKEYAMA Dai Tokushima Bunri University, 薬学部・薬学科, 講師 (20514821)
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|---|
| Co-Investigator(Renkei-kenkyūsha) |
KUZUHARA Takashi 徳島文理大学, 薬学部, 教授 (17370035)
ITO Etsuro 徳島文理大学, 香川薬学部, 教授 (80203131)
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| Project Period (FY) |
2009 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
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|---|
| Keywords | エピジェネティクス / メチル化シトシン / ヒストン / アセチル化 / ヒストン・アセチル化 / インフルエンザウイルス / RNAポリメラーゼ / PAサブユニット / PB2サブユニット / エンドヌクレアーゼ活性 / 昆虫 / 転写共役因子 |
|---|
| Research Abstract |
Although the aim of this study was to investigate the molecular mechanisms of translational coactivators in honeybees, we could not isolate these functional genes. Then, we changed the experimental targets with the RNA polymerases of influenza A virus, which has histone-acetylating activity as well as those of honeybee genes. We succeeded in cloning the target genes and expressing its recombinant proteins, which will be used for analyzing tertiary structure and functions.
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Report
(3 results)
Research Products
(25 results)
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[Journal Article] Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide2010
Author(s)
Iwai Y, Takahashi H, Hatakeyama D, Motoshima K, Ishikawa M, Sugita K, Hashimoto Y, Harada Y, Itamura S, Odagiri T, Tashiro M, Sei Y, Yamaguchi K, Kuzuhara T.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Contrary effects of octopamine receptor ligands on behavioral and neuronal changes in locomotion of Lymnaea2010
Author(s)
Miyamae Y, Komuro M, Murata A, Aono K, Nishikata K, Kanazawa A, Fujito Y, Komatsu T, Ito D, Abe T, Nagayama M, Uchida T, Gohara K, Murakami J, Kawai R, Hatakeyama D, Lukowiak K, Ito E.
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Journal Title
Biol Bull 218
Pages: 6-14
Related Report
Peer Reviewed
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