Project/Area Number |
20890011
|
Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
Allocation Type | Single-year Grants |
Research Field |
Metabolomics
|
Research Institution | Asahikawa Medical College |
Principal Investigator |
FUJITA Yukihiro Asahikawa Medical College, 医学部, 助教 (20451461)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
|
Keywords | インクレチン / GIP / GLP-1 / 転写因子 / 小腸糖代謝 / 甘味受容体 / 小腸 / 糖代謝 |
Research Abstract |
Two transcription factors Pdx1 and Pax6 play pivotal roles for GIP gene regulation. Some reports showed that the sweet taste receptor is involved in sugar-induced incretin secretion, however, we indicated that sweeteners, which surly bind to the receptor, do not enhance incretin release in rats.
|