Budget Amount *help |
¥2,418,000 (Direct Cost: ¥1,860,000、Indirect Cost: ¥558,000)
Fiscal Year 2009: ¥1,248,000 (Direct Cost: ¥960,000、Indirect Cost: ¥288,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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Research Abstract |
Myeloid-associated immunoglobulin-like receptor (MAIR)-I is expressed on most myeloid lineage cells and regulates the activation of these cells. Here we showed that decreased mortality in MAIR-I-deficient mice with experimental peritonitis-sepsis. Because sepsis is the systemic inflammatory syndrome induced by severe infections, remains a leading cause of death worldwide, these results suggest that MAIR-I is a novel molecular target for the treatment of sepsis.
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