morphologic and epigenetic study on the effects of child abuse on brain development
| Project/Area Number |
20890033
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Legal medicine
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| Research Institution | Gunma University (2009)
University of Toyama (2008) |
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Principal Investigator |
SANO Rie Gunma University, 大学院・医学系研究科, 助教 (70455955)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥1,664,000 (Direct Cost: ¥1,280,000、Indirect Cost: ¥384,000)
Fiscal Year 2009: ¥156,000 (Direct Cost: ¥120,000、Indirect Cost: ¥36,000)
Fiscal Year 2008: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
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| Keywords | 子どもの虐待 / DNAメチル化 / エピジェネティック / 虐待 / 小児 / 脳 |
|---|
| Research Abstract |
To investigate the effect on the brain of child abuse, we studied whether childhood abuse alters pattern of DNA methylation of genes. We examined Age-dependent DNA methylation of genes by Pyrosequencing method and compared with child abuse victim.
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Report
(3 results)
Research Products
(26 results)
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[Journal Article] Development of a Sensitive Enzyme-Linked Immunosorbent Assay for Measurement of DNase I in Human Serum2009
Author(s)
Nakajima T, Takagi-R, Tajima Y, Makita C, Kominato Y, Kuribara J, Ohshima S, Tada H, Tsurugaya H, Kobayashi Y, Takeshita H, Kawai Y, Yasuda T.
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Journal Title
Clinica Chimica Acta 403
Pages: 219-222
Related Report
Peer Reviewed
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[Journal Article] Development of a sensitive enzyme-linked immunosorbent assay for measurement of DNase I in human serum.2009
Author(s)
Nakajima T, Takagi R, Tajima Y, Makita C, Kominato Y, Kuribara J, Ohshima S, Tada H, Tsurugaya H, Kobayashi Y, Takeshita H, Kawai Y, Yasuda T.
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Journal Title
Clin Chim Acta. (in press)
Related Report
Peer Reviewed
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[Presentation] 低酸素による核酸分解酵素DNASEI遺伝子の転写調節2009
Author(s)
佐野利恵, 中島たみ子, 小湊慶彦, 加藤恵理子, 高士祐一, 山根庸弘, 新田みなみ, 藤原純子, 竹下治男, 植木美鈴, 安田年博
Organizer
日本DNA多型学会第18回学術集会
Place of Presentation
久留米
Related Report
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[Presentation] 核酸分解酵素DNase I遺伝子の転 写調節機構の解明2008
Author(s)
高木利恵, 中島たみ子, 小湊慶彦, 加藤恵理子, 高士祐一, 山根庸弘, 新田みなみ, 藤原純子, 竹下治男, 植木美鈴, 安田年博
Organizer
日本DNA多型学会第17回学術集会
Place of Presentation
東京
Related Report
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[Presentation] 核酸分解酵素DNaseI遺伝子の転写調節機構の解明2008
Author(s)
高木利恵,中島たみ子,小湊慶彦,加藤恵理子,高士祐一,山根庸弘,新田みなみ,藤原純子,竹下治男,植木美鈴,安田年博
Organizer
日本DNA多型学会第17回学術集会
Place of Presentation
東京
Related Report
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