The improvement of establishment efficiency and the induction to iPS cells of human dental pulp stem cells
| Project/Area Number |
20890091
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
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|---|
| Research Institution | Gifu University |
|---|
Principal Investigator |
KAWAGUCHI Tomoko Gifu University, 医学部附属病院, 医員 (30509815)
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|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,534,000 (Direct Cost: ¥1,180,000、Indirect Cost: ¥354,000)
Fiscal Year 2008: ¥1,768,000 (Direct Cost: ¥1,360,000、Indirect Cost: ¥408,000)
|
|---|
| Keywords | 歯学 / 組織幹細胞 / 歯髄 |
|---|
| Research Abstract |
低酸素分圧下での培養により、ヒト歯髄組織幹細胞(DPSC)は高い増殖能を呈し、高齢者からの樹立効率が向上した。また、iPS細胞への誘導においては、従来の4因子、3因子を用いた方法でDPSCからiPS細胞を誘導できた。誘導効率は皮膚線維芽細胞に比べて大きく改善した。
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] Dental Pulp Cells as Source for iPS Cell Banks2010
Author(s)
N. Tamaoki, K. Takahashi, T. Tanaka, T. Ichisaka, T. Takeda-Kawaguchi, K. Iida, T. Kunisada, T. Shibata, S. Yamanaka, H. Aoki, K. Tezuka
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Journal Title
Related Report
Peer Reviewed
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