Novel strategy of treatment for end-stage pulmonary emphysema by stem cell sheet drived from human adipose tissue
Project/Area Number |
20890118
|
Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
Allocation Type | Single-year Grants |
Research Field |
Thoracic surgery
|
Research Institution | Osaka University |
Principal Investigator |
SHIGEMURA Norihisa Osaka University, 医学系研究科, 助教 (30505508)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,016,000 (Direct Cost: ¥2,320,000、Indirect Cost: ¥696,000)
Fiscal Year 2009: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
Fiscal Year 2008: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
|
Keywords | 肺気腫 / 細胞シート治療 / 肺の再生医学 / アポトーシス / High Resolution CT / 呼吸不全 / 再生医療 / ティッシューエンジニアリング |
Research Abstract |
Through the pilot study using canine emphysema models, we successfully demonstrated that cell based therapy using myoblast cell sheet techniques improved emphysematous changes functionally and radiographycally. We will continue to work on the study to figure out the mechanism involved in this improvement.
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Report
(3 results)
Research Products
(1 results)