Novel strategy of treatment for end-stage pulmonary emphysema by stem cell sheet drived from human adipose tissue

Research Project

Project/Area Number	20890118
Research Category	Grant-in-Aid for Young Scientists (Start-up)
Allocation Type	Single-year Grants
Research Field	Thoracic surgery
Research Institution	Osaka University
Principal Investigator	SHIGEMURA Norihisa Osaka University, 医学系研究科, 助教 (30505508)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥3,016,000 (Direct Cost: ¥2,320,000、Indirect Cost: ¥696,000) Fiscal Year 2009: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000) Fiscal Year 2008: ¥1,508,000 (Direct Cost: ¥1,160,000、Indirect Cost: ¥348,000)
Keywords	肺気腫 / 細胞シート治療 / 肺の再生医学 / アポトーシス / High Resolution CT / 呼吸不全 / 再生医療 / ティッシューエンジニアリング
Research Abstract	Through the pilot study using canine emphysema models, we successfully demonstrated that cell based therapy using myoblast cell sheet techniques improved emphysematous changes functionally and radiographycally. We will continue to work on the study to figure out the mechanism involved in this improvement.

Report

(3 results)