Protection for inner ear against noise injury and aging by heat shock response
| Project/Area Number |
20890146
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Yamaguchi University |
|---|
Principal Investigator |
MIKURIYA Takefumi Yamaguchi University, 医学部附属病院, 助教 (00467797)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2009: ¥1,534,000 (Direct Cost: ¥1,180,000、Indirect Cost: ¥354,000)
Fiscal Year 2008: ¥1,716,000 (Direct Cost: ¥1,320,000、Indirect Cost: ¥396,000)
|
|---|
| Keywords | 内耳保護 / 老人性難聴 / 音響障害 / 熱ショック応答 / 老人性難徳 |
|---|
| Research Abstract |
Heat shock protein inducer protect against noise injury in guinea pig and mice. In this response, the pattern of induction of Hsp is interestingly different from other organs. Moreover this reagent prevent age related hearing loss and loss of sensory neuron. These results indicate that heat shock response in inner ear is vital response.
|
Report
(3 results)
Research Products
(13 results)
