Identification and characterization of novel muscle-derived cardio protective factors
| Project/Area Number |
20890170
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Kumamoto University |
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Principal Investigator |
IZUMIYA Yasuhiro Kumamoto University, 大学院・生命科学研究部, 助教 (10515414)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
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| Keywords | 骨格筋 / 心血管保護 / 分泌因子 |
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| Research Abstract |
We screened to identify novel muscle-derived factors that act on cardiovascular systems. We found that fibroblast growth factor-21 (FGF-21) and follistatin-like 1 (Fstl1) are a novel myokine that confers cardiovascular protection. Increasing in skeletal muscle mass, such as resistance training exercise, could be a useful treatment for cardiovascular diseases through production of cardiovascular protective myokines.
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Report
(3 results)
Research Products
(18 results)
