| Budget Amount *help |
¥2,977,000 (Direct Cost: ¥2,290,000、Indirect Cost: ¥687,000)
Fiscal Year 2009: ¥1,352,000 (Direct Cost: ¥1,040,000、Indirect Cost: ¥312,000)
Fiscal Year 2008: ¥1,625,000 (Direct Cost: ¥1,250,000、Indirect Cost: ¥375,000)
|
|---|
| Research Abstract |
The purpose of this study is to search the way to accelerate epithelization on surface of inner lumen of an artificial trachea, which had been clinically applied to surgical reconstructions of trachea or larynx. In this study, we developed several kind of bio-engineered trachea consist of fibroblasts, epithelial cells and the artificial trachea. Heterotopic dermal fibroblasts were useful for those accessibility compared to tracheal fibroblasts. After reconstruction of defects of rats' trachea and larynx with bio-engineered trachea, rapid maturity and differentiation of epithelium were observed.
|
