Does direct delivery of nitric oxide synthase improve acute limb ischemia?
| Project/Area Number |
20890199
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
HATADA Atsutoshi Wakayama Medical University, 医学部, 助教 (70508027)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2009: ¥1,404,000 (Direct Cost: ¥1,080,000、Indirect Cost: ¥324,000)
Fiscal Year 2008: ¥1,586,000 (Direct Cost: ¥1,220,000、Indirect Cost: ¥366,000)
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| Keywords | 急性動脈閉塞 / 一酸化窒素合成酵素 / 蛋白質療法 / 下肢壊死 / タンパク質導入 / タンパク質治療 |
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| Research Abstract |
It was successful that direct delivery of nitric oxide synthase into ischemic limb tissue in acute limb ischemia rat model. The type of targeted delivery system presented here should be broadly useful for administering therapeutic proteins to the acute limb ischemia.
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Report
(3 results)
Research Products
(1 results)
