A basic study of periodontal tissues regeneration by periodontal ligament specific gene, "F-spondin".

Research Project

Project/Area Number	20890245
Research Category	Grant-in-Aid for Young Scientists (Start-up)
Allocation Type	Single-year Grants
Research Field	Periodontal dentistry
Research Institution	Matsumoto Dental University
Principal Investigator	NISHIDA Eisaku Matsumoto Dental University, 歯学部, 助教 (10512519)
Project Period (FY)	2008 – 2009
Project Status	Completed (Fiscal Year 2009)
Budget Amount *help	¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000) Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	歯周病 / 歯根膜 / 創薬 / 再生 / 歯小嚢
Research Abstract	F-spondin, a specific dental follicle cell gene can play a important role during periodontal ligament development via TGF-b. It became clear that F-spondin guided the type I collagen and type XII collagen expression of periodontal ligament cell by overexpression and knockdown experiment. Thus, F- spondin can control the form of the collagen matrix in the tooth development.

Report

(3 results)