| Project/Area Number |
20890273
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biological pharmacy
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
ECHIGO Noriko Tokushima Bunri University, 薬学部, 助教 (80510130)
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| Research Collaborator |
MORIYAMA Yoshinori 岡山大学, 大学院・医歯薬学総合研究科, 教授
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
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| Keywords | 脳・神経 / 神経科学 / ATP / 薬学 / 神経科学当 / VNUT |
|---|
| Research Abstract |
ATP is major chemical transmitter in purinergic signal transmission, and vesicular nucleotide transmitter (VNUT) is responsible for ATP uptake by vesicle. I investigated localization and function of VNUT. VNUT is localized to various tissues existed in ATP signaling. Especially, in hippocampal neurons ATP is released from excitatory and inhibitory nerve terminals depend on VNUT. Thus, ATP may play a role of modulator in synaptic transmission.
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