Project/Area Number |
20890291
|
Research Category |
Grant-in-Aid for Young Scientists (Start-up)
|
Allocation Type | Single-year Grants |
Research Field |
Public health/Health science
|
Research Institution | National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East |
Principal Investigator |
SHIMAZU Taichi National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 予防研究部, 研究員 (00466202)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥3,302,000 (Direct Cost: ¥2,540,000、Indirect Cost: ¥762,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,742,000 (Direct Cost: ¥1,340,000、Indirect Cost: ¥402,000)
|
Keywords | 肺癌 / イソフラボン / 疫学 / コホート研究 / 癌 |
Research Abstract |
1) We investigated the association between isoflavone intake and lung cancer risk in a prospective cohort study. Isoflavone intake may be associated with a decreased risk of lung cancer in never smokers only. 2) We conducted a nested case-control study among women within the cohort, and found an inverse association between plasma level of genistein and lung cancer risk. The associations of isoflavone assessed by different methods with a decreased risk of lung cancer support the possibility that isoflavone is a preventive factor of lung cancer.
|