| Project/Area Number |
20F20753
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Single-year Grants |
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| Section | 外国 |
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| Review Section |
Basic Section 64010:Environmental load and risk assessment-related
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| Research Institution | National Institute for Environmental Studies |
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Principal Investigator |
遠藤 智司 国立研究開発法人国立環境研究所, 環境リスク・健康領域, 主任研究員 (30748934)
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| Co-Investigator(Kenkyū-buntansha) |
FISCHER FABIAN 国立研究開発法人国立環境研究所, 環境リスク・健康領域, 外国人特別研究員
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| Project Period (FY) |
2020-07-29 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2021: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2020: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | Chemical fate / Bioavailability / Bioaccumulation / Diffusion / Passive dosing / Toxicity |
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| Outline of Research at the Start |
The project aims to bridge the gap between lab and field. The chemical bioavailability in sediment contact tests depends on (1) the extent of binding to sediment and food sources; (2) continuous losses to water refreshment; and (3) the contribution of multiple exposure pathways to the total chemical uptake. In this project, exposure concentrations and uptake rates of organisms will be evaluated and related to toxicity using new measurement techniques such as passive dosing methods and computational kinetic models.
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| Outline of Annual Research Achievements |
The goal of this research project was to bridge the gap between the laboratory and the field with respect to chemical exposure and toxicity to benthic organisms. In this work, we developed both experimental and computational approaches to better understand the actual chemical exposure of test organisms in laboratory toxicity testing. A mechanistically based mass transport model was established that accounted for diffusion, sorption, dilution, and colloid-facilitated transport of chemicals in the spiked-sediment exposure system. The model successfully reproduced experimental concentration data and was used to quantitatively estimate the influences of chemical, sediment, and system properties on the mass distributions of chemicals. Comparison of the model and experimental results indicated a crucial role of dissolved organic matter (DOM) in the transport of hydrophobic chemicals. In addition, the passive dosing method using polymer meshes was developed and optimized to set up a consistent exposure condition. Toxicity tests with a set of chemicals with varying properties proved the robustness, repeatability, and applicability of the method. The influences of DOM in water on the toxicity of hydrophobic chemicals to a benthic invertebrate species were confirmed using the developed method. The result suggests that DOM plays an important role and should be considered when assessing toxicity to benthic organisms.
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| Research Progress Status |
令和3年度が最終年度であるため、記入しない。
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| Strategy for Future Research Activity |
令和3年度が最終年度であるため、記入しない。
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