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Proposal of brain medical evidence for the continuation or surrender of driver's licenses for the elderly

Research Project

Project/Area Number 20H00267
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Review Section Medium-sized Section 22:Civil engineering and related fields
Research InstitutionKochi University of Technology

Principal Investigator

Park Kaechang  高知工科大学, 地域連携機構, 客員教授 (60333514)

Co-Investigator(Kenkyū-buntansha) 吉田 真一  高知工科大学, 情報学群, 教授 (30334519)
沖田 学  高知工科大学, 地域連携機構, 客員研究員 (80816934)
繁桝 博昭  高知工科大学, 情報学群, 教授 (90447855)
山下 典生  岩手医科大学, 医歯薬総合研究所, 准教授 (90628455)
Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥44,980,000 (Direct Cost: ¥34,600,000、Indirect Cost: ¥10,380,000)
Fiscal Year 2023: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2022: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2021: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2020: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
KeywordsMRI / 高齢ドライバー / 交通事故対策 / 白質病変 / 脳萎縮 / 灰白質脳部位 / 事故対策 / MCI / 運転免許更新 / 認知機能 / 交通事故 / 高齢者 / 運転免許 / 実車運転 / 機械学習 / 実車運転評価 / 運転免許制度 / 免許更新 / 運転免許の継続・返納
Outline of Research at the Start

本研究では、認知機能検査が義務化されている75歳以上の高齢者講習受講者から、① 講習時での認知機能検査成績、教官による実車運転操作時の評価データ、実車運転操作時の車両データ(CANデータ)に加えて、新たに② 臨床医学用認知機能検査バッテリーデータ、事故や誤進入歴等のアンケート調査データ、脳MRIデータをマルチモダール学習データとして、高齢ドライバーの危険運転行動を高精度予測できる機械学習を開発する。さらに③高齢ドライバー支援を目的とした認知リハビリテーション介入を行う自動車運転外来から、経時的学習データを得て上記機械学習の検証作業を行う。

Outline of Final Research Achievements

We analyzed the relationship between safe driving skills and brain features (white matter lesion volume and brain atrophy) in elderly drivers at a driving school. White matter lesion volume in the parietal lobe was significantly correlated with a decline in driving skill scores when turning right, regardless of age, through a decline in dynamic visual recognition, while brain atrophy and white matter lesion volume in the occipital lobe caused the similar effect on driving skill during turning right without involving in dynamic visual recognition.

Using large-scale MRI data from a brain checkup, we investigated the relationship between past traffic accident history and brain features using a machine learning battery, and obtained the precision and recall of prediction performance of traffic accidents due to brain factors. It was shown that MRI brain testing may be able to identify elderly drivers with poor driving skills or a high probability of causing traffic accidents in advance.

Academic Significance and Societal Importance of the Research Achievements

高齢者の悲惨な交通事故が国家的喫緊課題となって久しいが、その有効な対策は未だ確立されていない。2060年までの約40年間、日本は高齢化率で世界のトップクラスを維持すると言われている。小手先ではなく、科学的に裏付けられた抜本的な日本の高齢者対策を世界が固唾をのんで見守っているのである。
本研究により、MRIで計測可能な脳特徴量(脳萎縮と白質病変)から、交通事故や危険運転をする高齢ドライバーを事前に同定できる方法論を提唱することが可能になった。今後は、脳ドックで得られる聞き取り調査に加えて、実際の事故当事者から検証できれば、高齢ドライバー対策としてMRI事前判別法は大きな福音になるであろう。

Report

(6 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Comments on the Screening Results   Annual Research Report
  • Research Products

    (13 results)

All 2024 2023 2022 2021 2020

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 3 results) Presentation (6 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Book (1 results)

  • [Journal Article] Uniformly positive or negative correlation of cerebral gray matter regions with driving safety behaviors of healthy older drivers2024

    • Author(s)
      Park Kaechang、Putra Handityo Aulia、Yoshida Shinichi、Yamashita Fumio、Kawaguchi Atsushi
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-023-50895-7

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adult attention-deficit/hyperactivity disorder traits in healthy adults associated with brain volumetric data identify precuneus involvement in traffic crashes2023

    • Author(s)
      Putra Handityo Aulia、Park Kaechang、Oba Hikaru、Yamashita Fumio
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 1-8

    • DOI

      10.1038/s41598-023-49907-3

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Leukoaraiosis Predicts Wrong-Way Entry and Near One on Highways for Healthy Drivers2023

    • Author(s)
      Kaechang Park、Yoshinori Nakagawa
    • Journal Title

      Journal of Neurological Disorders

      Volume: 11 Pages: 1-4

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Parietal and occipital leukoaraiosis due to cerebral ischaemic lesions decrease the driving safety performance of healthy older adults2022

    • Author(s)
      Oba Hikaru、Park Kaechang、Yamashita Fumio、Sato Shinichi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 21436-21436

    • DOI

      10.1038/s41598-022-25899-4

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Aging Brains degrade driving safety performances of the healthy elderly2022

    • Author(s)
      Kaechang Park, Kazumi Renge, Yoshinori Nakagawa, Fumio Yamashita, Masahiro Tada and Yasuhiko Kumagai
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: 13 Pages: 1-11

    • DOI

      10.3389/fnagi.2021.783717

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mild functional decline and driving performance of older drivers without a diagnosed dementia: Study of leukoaraiosis and cognitive function2020

    • Author(s)
      Renge Kazumi、Park Kaechang、Tada Masahiro、Kimura Toshiaki、Imai Yasuo
    • Journal Title

      Transportation Research Part F: Traffic Psychology and Behaviour

      Volume: 75 Pages: 160-172

    • DOI

      10.1016/j.trf.2020.09.016

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 脳加齢現象である白質病変を有する高齢ドライバーの実車運転行動解析2023

    • Author(s)
      朴啓彰
    • Organizer
      第25回日本老年行動科学会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 無症候性白質病変と安全運転の関係2023

    • Author(s)
      朴啓彰
    • Organizer
      第32回日本脳ドック学会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 白質病変:人生百年時代における脳ドック診療の担い手2022

    • Author(s)
      朴啓彰
    • Organizer
      第31回日本脳ドック学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 無症候性白質病変と高齢ドライバーの実車運転パフォーマンス2022

    • Author(s)
      朴啓彰
    • Organizer
      第56回日本交通科学学会・学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Aging brain and driving safety performances2021

    • Author(s)
      Kaechang Park, Yasuhiko Kumagai
    • Organizer
      ITS world congress
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 軽度認知機能障害を呈した 高齢ドライバー症例への運転リハによる 安全運転の維持・向上に関する中長期報告2020

    • Author(s)
      朴啓彰、沖田学、佐藤誠、鎌倉航平
    • Organizer
      ITS シンポジウム
    • Related Report
      2020 Annual Research Report
  • [Book] 75歳を越えても安全運転できる運転脳を鍛える本2024

    • Author(s)
      朴啓彰
    • Total Pages
      304
    • Publisher
      アスコム
    • Related Report
      2023 Annual Research Report

URL: 

Published: 2020-04-28   Modified: 2025-01-30  

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