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Artificial Vision

Research Project

Project/Area Number 20H00606
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Review Section Medium-sized Section 61:Human informatics and related fields
Research InstitutionOsaka University (2022-2024)
Fukui University of Technology (2020-2021)

Principal Investigator

Yagi Tetsuya  大阪大学, 国際医工情報センター, 招へい教授 (50183976)

Co-Investigator(Kenkyū-buntansha) 石井 和男  九州工業大学, 大学院生命体工学研究科, 教授 (10291527)
林田 祐樹  三重大学, 工学研究科, 教授 (10381005)
武内 良典  近畿大学, 理工学部, 教授 (70242245)
廣瀬 哲也  大阪大学, 大学院工学研究科, 教授 (70396315)
高橋 啓介  愛知淑徳大学, 健康医療科学部, 教授 (80236273)
末松 尚史  大阪大学, 工学研究科, 助教 (30779517)
Project Period (FY) 2020-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2024)
Budget Amount *help
¥44,330,000 (Direct Cost: ¥34,100,000、Indirect Cost: ¥10,230,000)
Fiscal Year 2023: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2022: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2021: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2020: ¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
Keywords視覚再建 / 人工視覚 / 視覚野電気刺激 / ニューロモーフィック / 画像処理 / 画像通信 / 低消費電力 / 光覚シミュレーション / ブレインコンピュータインターフェイス / 低消費電力化 / ニューロモーフィック網膜 / ニューロモーフィック通信 / 光覚パターン / シリコン網膜 / 画像圧縮 / 画像無線通信 / 皮質電気刺激 / 画像情報圧縮 / 画像情報通信 / 網膜 / 視覚情報符号化 / 無線通信 / スパイクニューロン / 脳刺激型人工視覚 / 心理物理実験 / 人工視覚補綴
Outline of Research at the Start

脳刺激型人工視覚(以下人工視覚)は、失明者の視覚野を多点で電気刺激することにより、視覚機能を部分的にも再建するという未来の失明治療法である。本研究において、視覚の初期過程における情報処理、符号化および通信様式を工学的に理解し、申請者が開発したアナログ人工網膜と、視神経における画像符号化・通信の原理を組み合わせた全く新しい前臨床段階の人工視覚を完成させ、心理物理学実験によりその性能を評価する。

Outline of Final Research Achievements

The artificial vision with cortical micro-stimulation is a future clinical treatment to partially restore vision in blind people with the aid of electrical devices implanted under the scalp. The artificial vision models developed so far have been designed based on conventional digital image processing and communication technologies, confronting with excessive power and heat dissipation. To overcome this problem, we propose a novel design of the artificial vision that inspired by an architecture/algorithm of computation and communication in the visual neuronal networks of the retina and the primary visual cortex (this design is referred to as neuromorphic artificial vision). We partially implemented the architecture/algorithm with integrated circuits and confirmed the low power operation of the NM artificial vision. The feasibility and usefulness of the NM artificial vision with regard to clinical application were demonstrated by real time simulation of expected phosphene patterns.

Academic Significance and Societal Importance of the Research Achievements

センサーやコンピュータと脳神経ネットワークを、集積電子デバイスを介して直接交信させる技術(ブレインインコンピュータターフェース、略してBCI)は、失われた脳機能の再建治療のみならず、未来の情報通信手段としても注目されている。しかしながら現在のBCIは基本的に逐次デジタル信号処理・通信の技術をベースとして設計されており、脳神経ネットワークとの相性がよ悪いのみならず、完全埋植型BCIでは、電力供給や発熱という問題がある。本研究で示した人工視覚は、視覚神経の構造と計算アルゴリズムを取り入れ、これらの問題を軽減しBCI設計に新たな指針を与える。加えて新しい画像情報の処理・通信法としても応用できる。

Report

(6 results)
  • 2024 Final Research Report ( PDF )
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Comments on the Screening Results   Annual Research Report
  • Research Products

    (31 results)

All 2024 2023 2022 2021

All Journal Article (15 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 13 results,  Open Access: 5 results) Presentation (16 results) (of which Int'l Joint Research: 6 results,  Invited: 2 results)

  • [Journal Article] Sub-60-mV Charge Pump and its Driver Circuit for Extremely Low-Voltage Thermoelectric Energy Harvesting2024

    • Author(s)
      SEBE Hikaru、KANEMOTO Daisuke、HIROSE Tetsuya
    • Journal Title

      IEICE Transactions on Electronics

      Volume: E107.C Issue: 10 Pages: 400-407

    • DOI

      10.1587/transele.2023CTP0005

    • ISSN
      0916-8524, 1745-1353
    • Year and Date
      2024-10-01
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Programmable Differential Bandgap Reference Circuit for Ultra-Low-Power CMOS LSIs2024

    • Author(s)
      ITOTAGAWA Yoshinori、ATSUMI Koma、SEBE Hikaru、KANEMOTO Daisuke、HIROSE Tetsuya
    • Journal Title

      IEICE Transactions on Electronics

      Volume: E107.C Issue: 10 Pages: 392-399

    • DOI

      10.1587/transele.2023CTP0004

    • ISSN
      0916-8524, 1745-1353
    • Year and Date
      2024-10-01
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sub-50 mV power supply, recursive stacking body bias NAND gate for extremely low-voltage CMOS LSIs2024

    • Author(s)
      Sumi Shintaro、Sebe Hikaru、Kanemoto Daisuke、Hirose Tetsuya
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 63 Issue: 3 Pages: 03SP87-03SP87

    • DOI

      10.35848/1347-4065/ad29ea

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ultra-low power low-dropout linear regulator with a load current tracking bias current generator for loT devices2024

    • Author(s)
      Mizuno Yosuke、Sebe Hikaru、Kanemoto Daisuke、Hirose Testuya
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 63 Issue: 2 Pages: 02SP96-02SP96

    • DOI

      10.35848/1347-4065/ad202e

    • Related Report
      2023 Annual Research Report 2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] On the spatial synaptic propagation of excitations induced by repetitive microstimulation pulses in the mouse visual cortex2024

    • Author(s)
      Santa Fukuda, Tomohiro Nomoto, Tetsuya Yagi, Yuki Hayashida
    • Journal Title

      Proceedings of 6th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

      Volume: -

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CODEC system using EG2C chips and power control with a sleep mode for a visual prosthesis2024

    • Author(s)
      Naoya Tanaka, Shogo Hirayama and Yoshinori Takeuchi
    • Journal Title

      Proceedings of The 25th Workshop on Synthesis And System Integration of Mixed Information Technologies

      Volume: - Pages: 335-340

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of the inter-phase delay of microstimulation pulses on the spatio-temporal neural excitation in the mouse visual cortex in vitro2023

    • Author(s)
      Santa Fukuda, Tomohiro Nomoto, Tetsuya Yagi, Yuki Hayashida
    • Journal Title

      Proceedings of 11th International IEEE EMBS Conference on Neural Engineering

      Volume: article#81422

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sub-30-mV-Supply, Fully Integrated Ring Oscillator Consisting of Recursive Stacking Body-Bias Inverters for Extremely Low-Voltage Energy Harvesting2023

    • Author(s)
      H. Sebe, T. Okumura, S. Sumi, D. Kanemoto P. -H. Chen, T. Hirose
    • Journal Title

      Proceedings of ESSCIRC 2023- IEEE 49th European Solid State Circuits Conference (ESSCIRC)

      Volume: - Pages: 325-328

    • DOI

      10.1109/esscirc59616.2023.10268819

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] オペコードコンパクト化によるプロセッサの回路面積低減の評価2023

    • Author(s)
      吉澤翔悟、武内良典
    • Journal Title

      DAシンポジウム2023論文集

      Volume: 123 Pages: 71-77

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 視覚野刺激型人工視覚システムの刺激データに対する圧縮プロセッサ設計2023

    • Author(s)
      平山聖冴,田中尚哉,武内良典
    • Journal Title

      情処研報

      Volume: SLDM-201, No.7 Pages: 90-96

    • Related Report
      2021 Annual Research Report
  • [Journal Article] 人工視覚システムのデータ圧縮伸長モジュールのFPGA実装2023

    • Author(s)
      田中尚哉,平山聖冴,武内良典
    • Journal Title

      情処研報

      Volume: SLDM-201, No.8, Pages: 97-102

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Multichannel stimulation module as a tool for animal studies on cortical neural prostheses2022

    • Author(s)
      Hayashida Yuki、Kameda Seiji、Umehira Yuichi、Ishikawa Shinnosuke、Yagi Tetsuya
    • Journal Title

      Frontiers in Medical Technology

      Volume: 4

    • DOI

      10.3389/fmedt.2022.927581

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A bench-test system of the visual prostheses utilizing retino-morphic spikes as the driver signals of intracortical microstimulation2022

    • Author(s)
      Ryosuke Okada, Shinnosuke Ishikawa, Tetsufumi Tasaki, Tetsuya Yagi, Yuki Hayashida
    • Journal Title

      Proceedings of the 2022 International Conference on Artificial Life and Robotics

      Volume: - Pages: 524-528

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A 35-mV supply ring oscillator consisting of stacked body bias inverters for extremely low-voltage LSIs2021

    • Author(s)
      Nishi Masaya、Matsumoto Kaori、Kuroki Nobutaka、Numa Masahiro、Sebe Hikaru、Matsuzuka Ryo、Maida Osamu、Kanemoto Daisuke、Hirose Tetsuya
    • Journal Title

      IEICE Electronics Express

      Volume: 18 Issue: 6 Pages: 20210065-20210065

    • DOI

      10.1587/elex.18.20210065

    • NAID

      130008003169

    • ISSN
      1349-2543
    • Year and Date
      2021-03-25
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Accumulation of non-synaptic and synaptic excitations induced by microstimulation pulses in the mouse visual cortex layer II/II2021

    • Author(s)
      Santa Fukuda, Tomohiro Nomoto, Kou Yoshida, Yuki Hayashida, Tetsuya Yagi
    • Journal Title

      Proceedings of the 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society

      Volume: - Pages: 5164-5164

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Presentation] On the spatial synaptic propagation of excitations induced by repetitive microstimulation pulses in the mouse visual cortex2024

    • Author(s)
      Fukuda Santa、Nomoto Tomohiro、Yagi Tetsuya、Hayashida Yuki
    • Organizer
      46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 15-19, 2024, Orlando FL, USA.
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] On the Information Coding with Retinal Neuromorphic Spikes Toward the Spike-Based Microstimulation in Intra-Cortical Visual Prostheses2024

    • Author(s)
      Nokura Tomoya、Tamaki Taiga、Hayashida Yuki
    • Organizer
      2024 16th Biomedical Engineering International Conference (BMEiCON), Chon Buri, Thailand
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] CODEC system using EG2C chips and power control with a sleep mode for a visual prosthesis2024

    • Author(s)
      Naoya Tanaka, Shogo Hirayama and Yoshinori Takeuchi
    • Organizer
      The 25th Workshop on Synthesis And System Integration of Mixed Information Technologies
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neuromorphic design of cortical visual prosthesis2024

    • Author(s)
      T. Yagi, Y. Hayashida, Y. Takeuchi
    • Organizer
      The 12th RIEC International Symposium on Brain Functions and Brain Computer
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 災害環境での診断・健康管理のための情報通信技術2024

    • Author(s)
      八木哲也
    • Organizer
      第63回日本生体医工学会大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Neuromorphic design of cortical visual prosthesis2024

    • Author(s)
      Tetsuya Yagi
    • Organizer
      The 12th Research Institute of Electrical Communication (RIEC) International Symposium on Brain Functions and Brain Computer
    • Related Report
      2022 Annual Research Report
  • [Presentation] Effects of the inter-phase delay of microstimulation pulses on the spatio-temporal neural excitation in the mouse visual cortex in vitro2023

    • Author(s)
      Santa Fukuda, Tomohiro Nomoto, Tetsuya Yagi, Yuki Hayashida
    • Organizer
      11th International IEEE EMBS Conference on Neural Engineering
    • Related Report
      2023 Annual Research Report
  • [Presentation] 人工視覚システムのための圧縮伸張チップEG2Cの消費電力評価2023

    • Author(s)
      平山聖冴
    • Organizer
      電気電子情報通信学会 VLD研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 視覚神経系を模倣した脳刺激型人工視覚の開発2023

    • Author(s)
      八木哲也
    • Organizer
      第62回日本生体医工学会大会企画シンポジウム
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Use-Dependent Inactivation of the Mouse Visual Cortex in Response to Microstimulation Train2022

    • Author(s)
      Santa Fukuda, Kou Yoshida, Tomohiro Nomoto, Tetsuya Yagi, Yuki Hayashida
    • Organizer
      E-Health and Bioengineering Conference (EHB)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fully Integrated Switched-Capacitor Buck Converter with Variable Ratio and Frequency Controllers for Ultra-Low Power LSI Systems2022

    • Author(s)
      R. Matsuzuka, S. Kanzaki, K. Matsumoto, N. Kuroki, M. Numa, D. Kanemoto, T. Hirose
    • Organizer
      International Conference on Solid State Devices and Materials (SSDM 2022)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 大脳皮質への連続パルス微小刺激に対する蓄積的興奮応答のメカニズムに関する解析2021

    • Author(s)
      福田燦太, 野本知宏, 吉田 航, 林田祐樹, 八木哲也
    • Organizer
      2021年度 ME とバイオサネティックス研究会
    • Related Report
      2020 Annual Research Report
  • [Presentation] RISC-Vを用いた命令拡張のためのプロセッサ開発環境の検討2021

    • Author(s)
      中尾怜史, 武内良典
    • Organizer
      DAシンポジウム2021
    • Related Report
      2020 Annual Research Report
  • [Presentation] Rocket-Chipへの三角関数演算命令の実装と評価2021

    • Author(s)
      中尾怜史, 武内良典
    • Organizer
      デザインガイア
    • Related Report
      2020 Annual Research Report
  • [Presentation] 人工視覚装用者への視能訓練の有効性:人工視覚シミュレーターを用いた知覚再現実験2021

    • Author(s)
      本居快・杉浦巧知・國武実里・高橋啓介・髙橋伸子・松久保雄哉・八木哲也
    • Organizer
      第61回視能矯正学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 人工視覚:脳視覚系に学んだコンピュータの目2021

    • Author(s)
      八木哲也
    • Organizer
      電気学会北陸支部フロンティアセミナー
    • Related Report
      2020 Annual Research Report
    • Invited

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Published: 2020-04-28   Modified: 2026-01-16  

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