Invasion of antibiotic resistance genes persisting in aquatic environments to humans: invasion mechanisms and the risk

• Project/Area Number: 20H00633
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Medium-sized Section 63:Environmental analyses and evaluation and related fields
• Research Institution: Ehime University
• Principal Investigator: Suzuki Satoru 愛媛大学, 理工学研究科(工学系), 寄附講座教授 (90196816)
• Co-Investigator(Kenkyū-buntansha): 佐野 大輔 東北大学, 工学研究科, 教授 (80550368) ; 渡辺 幸三 愛媛大学, 沿岸環境科学研究センター, 教授 (80634435)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥44,980,000 (Direct Cost: ¥34,600,000、Indirect Cost: ¥10,380,000); Fiscal Year 2023: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000); Fiscal Year 2022: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000); Fiscal Year 2021: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000); Fiscal Year 2020: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
• Keywords: 薬剤耐性 / 環境微生物 / 水環境 / 遺伝子伝播 / 暴露リスク

Outline of Research at the Start

人獣医療現場で発生した薬剤耐性菌は，下水処理施設，河川から海へ流出する。環境に拡散した耐性菌は死滅・除去されると考えられてきたが，申請者らは，臨床由来の耐性菌が持つ耐性遺伝子が，環境の常在細菌群集に残存することを解明した。さらに，臨床では知られていない新規耐性遺伝子が海洋に存在することを明らかにしつつある。本研究では，残存実態解明からさらに進めて，臨床および水圏起源の耐性遺伝子が病原菌・腸内細菌に伝播するプロセスを解析し，水圏から人間環境へ耐性遺伝子が侵入する機構・条件を解明し，リスク評価を目指す。遺伝子伝播と侵入の機構を解明する研究であり，ワンヘルスに環境視点で貢献する。

Outline of Final Research Achievements

The promotion of the transfer of antimicrobial resistance genes (ARGs) from aquatic bacteria to E. coli by organic matter, and the discovery of new ARGs and transfer factors, suggest the possibility of gene transfer in treated water drains and aquaculture farms, and convergence to specific transfer factors over time. It was revealed that ARGs in the hydrosphere can invade the human environment by flies. Acinetobacter, which is important as an opportunistic bacterium, has common ARGs between environmental and clinical strains, and environmental studies have suggested that it can spread between different environments. Finally, we built an ARGs propagation model and were able to contribute to environmental ARGs countermeasures from a One Health perspective.

Academic Significance and Societal Importance of the Research Achievements

環境調査と実験で、下水排出口、養殖場などが耐性遺伝子(ARGs)拡散のリスクポイントと示唆された。また、ハエを運び屋として水環境のARGsが人間環境に侵入できること、Acinetobacterでの環境・臨床間でARGsに共有性があった。これらは、医学、獣医学に加えて環境学視点からの新規知見であり、学術的に環境視点からのパイオニア成果と言える。さらに、バイオフィルム系でのARGs伝達モデルが構築され、耐性菌対策（衛生対策）への提案が可能になったことは、社会的にも貢献できる成果である。

Research Products

• [Int'l Joint Research] University of Malaya(マレーシア)
• [Journal Article] Resistomes in freshwater bioaerosols and their impact on drinking and recreational water safety: A perspective (2024)
  • Author(s): Saibu Salametu、Uhanie Perera Ishara、Suzuki Satoru、Rodo Xavier、Fujiyoshi So、Maruyama Fumito
  • Journal Title: Environment International Volume: 183 Pages: 108377-108377
  • DOI: 10.1016/j.envint.2023.108377
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Recommendations of key elements within an integrated monitoring framework of antimicrobial resistance for Asian countries (2024)
  • Author(s): Honda, R., Kumar, M., Mardalisa, Wang, R., Sabar, M. A., Chaminda, T., Sirikanchana, K., Makkeaw, P., Sulfikar, Ju, F., Jiang, G., Li, B., Chiemchaisri, C., Gomi, R., Amarasiri, M., Venter, H., Nishiyama, M., Watanabe, T., Ihara, M., Kasuga, I., Watanabe, K. and Suzuki, S.
  • Journal Title: Environmental Science & Technology Letters Volume: 11 (1) Issue: 1 Pages: 5-8
  • DOI: 10.1021/acs.estlett.3c00820
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Cellulolytic enzymes in <i>Microbulbifer</i> sp. Strain GL-2, a marine fish intestinal bacterium, with emphasis on endo-1,4-β-glucanases Cel5A and Cel8 (2024)
  • Author(s): Ohnishi Ken-ichiro、Watanabe Seiya、Kadoya Aya、Suzuki Satoru
  • Journal Title: The Journal of General and Applied Microbiology Volume: 70 Issue: 2 Pages: n/a
  • DOI: 10.2323/jgam.2024.03.001
  • ISSN: 0022-1260, 1349-8037
  • Peer Reviewed / Open Access
• [Journal Article] Persistence of Marine Bacterial Plasmid in the House Fly (Musca domestica): Marine-Derived Antimicrobial Resistance Genes Have a Chance of Invading the Human Environment (2024)
  • Author(s): Nawata Kanoko、Kadoya Aya、Suzuki Satoru
  • Journal Title: Microbial Ecology Volume: 87 Issue: 1 Pages: 30-30
  • DOI: 10.1007/s00248-023-02341-4
  • Peer Reviewed / Open Access
• [Journal Article] Artificial sweeteners in surface waters from Asian, African and Middle Eastern countries: Utility as molecular markers and water pollution status in 2010–2019 (2024)
  • Author(s): SUMIDA Tatsuya、TAKADA Hideshige、TAKEI Ayaka、YOSHIMATSU Kenji、IMAI Shota、KOIKE Tatsuya、BANNO Marin、FUJISAWA Miharu、ISOGAI Saya、ALIDOUST Mona、YEO Bee Geok、MIZUKAWA Kaoruko、TARAO Mitsunori、SUZUKI Satoru、KWAN Charita S.、Rinawati、OFOSU-ANIM John、SABI Edward Benjamin、 et al.
  • Journal Title: Environmental Monitoring and Contaminants Research Volume: 4 Issue: 0 Pages: 1-18
  • DOI: 10.5985/emcr.20230006
  • ISSN: 2435-7685
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Marine bacteria harbor the sul4 sulfonamide-resistance gene without mobile genetic elements (2023)
  • Author(s): Shindoh, S., Kadoya, A., Kanechi, R., Watanabe, K., Suzuki, S.
  • Journal Title: Frontiers in Microbiology Volume: 14 Pages: 1230548-1230548
  • DOI: 10.3389/fmicb.2023.1230548
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Contribution of ammonium oxidizing archaea and bacteria to intensive nitrification during summer in Mutsu Bay, Japan (2023)
  • Author(s): Aizawa Akari、Watanabe Yuka、Hashioka Kaori、Kadoya Aya、Suzuki Satoru、Yoshimura Takeshi、Kudo Isao
  • Journal Title: Regional Studies in Marine Science Volume: 63 Pages: 102984-102984
  • DOI: 10.1016/j.rsma.2023.102984
  • Peer Reviewed / Open Access
• [Journal Article] Short-term influences of flow alteration on microbial community structure and putative metabolic functions in gravel bar hyporheic zones (2023)
  • Author(s): Doloiras-Larano Arnelyn D.、Serrana Joeselle M.、Takahashi Shinji、Takemon Yasuhiro、Watanabe Kozo
  • Journal Title: Frontiers in Environmental Science Volume: 11 Pages: 125561-125561
  • DOI: 10.3389/fenvs.2023.1205561
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Editorial: Antibiotic resistance in aquatic systems, volume II (2023)
  • Author(s): Suzuki Satoru、Pruden Amy、Virta Marko、Zhang Tong
  • Journal Title: Frontiers in Microbiology Volume: 14 Pages: 1298681-1298681
  • DOI: 10.3389/fmicb.2023.1298681
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effect of Protists on Horizontal Transfer of Antimicrobial Resistance Genes in Water Environment (2023)
  • Author(s): Suzuki Satoru、Sano Daisuke
  • Journal Title: Journal of Water and Environment Technology Volume: 21 Issue: 2 Pages: 97-107
  • DOI: 10.2965/jwet.22-095
  • ISSN: 1348-2165
  • Peer Reviewed / Open Access
• [Journal Article] Bacterial Diversity and Antibiotic Resistance Genes Associated with the Different Farming Systems of Black Tiger Shrimp (Penaeus monodon) in Bangladesh (2023)
  • Author(s): Zakaria Md.、Sanyal Santonu K.、Haque Md. Inja-Mamun、Mandal Shankar Chandra、Watanabe Kozo、Hossain Anwar
  • Journal Title: Aquaculture Research Volume: 2023 Pages: 1-17
  • DOI: 10.1155/2023/6255586
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Microbial Community Structure and Bacterial Lineages Associated With Sulfonamides Resistance in Anthropogenic Impacted Larut River. (2022)
  • Author(s): Lye YL, Chai LC, Lee CW, Suzuki S, Bong CW
  • Journal Title: Water Volume: 14 Issue: 7 Pages: 1018-1018
  • DOI: 10.3390/w14071018
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Macrolide resistance genes and mobile genetic elements in waterways from pig farms to the sea in Taiwan (2022)
  • Author(s): Suzuki, S, Kadoya, A, Masuda, N, Sugimoto, Y, Takada, H, Mizukawa, K, Takei, A, Chou, H-Y, Wu, J-H
  • Journal Title: Journal of Global Antimicrobial Resistance Volume: 29 Pages: 360-370
  • DOI: 10.1016/j.jgar.2022.04.024
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] An Integrative and Conjugative Element (ICE) Found in <i>Shewanella halifaxensis</i> Isolated from Marine Fish Intestine May Connect Genetic Materials between Human and Marine Environments (2022)
  • Author(s): Sugimoto, Y, Kadoya, A, Suzuki, S
  • Journal Title: Microbes and Environments Volume: 37 Issue: 3 Pages: n/a
  • DOI: 10.1264/jsme2.ME22038
  • ISSN: 1342-6311, 1347-4405
  • Peer Reviewed / Open Access
• [Journal Article] Sediment-associated Microbial Community Profiling: Sample Pre-processing through Sequential Membrane Filtration for 16s rDNA Amplicon Sequencing (2022)
  • Author(s): Joeselle M. Serrana, Kozo Watanabe
  • Journal Title: BMC Microbiology Volume: 22(1) Issue: 1 Pages: 33-33
  • DOI: 10.1186/s12866-022-02441-0
  • Peer Reviewed / Open Access
• [Journal Article] Draft Genome Sequences of Putative Aerobic Anoxygenic Phototrophic Bacterial Strains <i>Jannaschia</i> sp. Strains AI_61 and AI_62, Isolated from Seawater around a Coastal Aquaculture Area (2021)
  • Author(s): Sato-Takabe Yuki、Nakajima Yu、Suzuki Satoru、Sekiguchi Kota、Hanada Satoshi、Shiozaki Takuhei
  • Journal Title: Microbiology Resource Announcements Volume: 10 Issue: 28 Pages: 1-2
  • DOI: 10.1128/mra.00491-21
  • Peer Reviewed / Open Access
• [Journal Article] Contamination of antibiotics and sul and tet(M) genes in veterinary wastewater, river, and coastal sea in Thailand (2021)
  • Author(s): Suzuki Satoru、Ogo Mitsuko、Takada Hideshige、Seki Kanako、Mizukawa Kaoruko、Kadoya Aya、Yokokawa Taichi、Sugimoto Yuta、Sato-Takabe Yuki、Boonla Chanchai、Anomasiri Wilai、Sukpanyatham Nop
  • Journal Title: Science of The Total Environment Volume: 791 Pages: 148423-148423
  • DOI: 10.1016/j.scitotenv.2021.148423
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Antibiotic residues from aquaculture farms and their ecological risks in Southeast Asia: A case study from Malaysia (2021)
  • Author(s): Ee Lean Thiang, Choon Weng Lee, Hideshige Takada, Kanako Seki, Ayaka Takei, Satoru Suzuki, Aijun Wang, Chui Wei Bong
  • Journal Title: Ecosystem Health and Sustainability Volume: 7 Issue: 1 Pages: 1-1
  • DOI: 10.1080/20964129.2021.1926337
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Adsorption of sulfonamides to marine diatoms and arthropods (2021)
  • Author(s): Rie Matsuura, Reina Kanehara, Aya Kadoya, Satoru Suzuki
  • Journal Title: Environmental Toxicology and Pharmacology Volume: 82 Pages: 103557-103557
  • DOI: 10.1016/j.etap.2020.103557
  • Peer Reviewed / Open Access
• [Journal Article] Induction of Extracellular Aminopeptidase Production by Peptides in Some Marine Bacterial Species (2021)
  • Author(s): Suzune Shindoh, Yumiko Obayashi, Satoru Suzuki
  • Journal Title: Microbes and Environments Volume: 36 Issue: 1 Pages: n/a
  • DOI: 10.1264/jsme2.ME20150
  • NAID: 130007997799
  • ISSN: 1342-6311, 1347-4405
  • Peer Reviewed / Open Access
• [Journal Article] Isolation of cellulase-producing <i>Microbulbifer</i> sp. from marine teleost blackfish (<i>Girella melanichthys</i>) intestine and the enzyme characterization (2021)
  • Author(s): Daiki Tanaka, Ken-ichiro Ohnishi, Seiya Watanabe, Satoru Suzuki
  • Journal Title: The Journal of General and Applied Microbiology Volume: 67 Issue: 2 Pages: 47-53
  • DOI: 10.2323/jgam.2020.05.001
  • NAID: 130008047931
  • ISSN: 0022-1260, 1349-8037
  • Peer Reviewed / Open Access
• [Journal Article] Profiling the Microbial Community Structure and Functional Diversity of a Dam-regulated River Undergoing Gravel Bar Restoration (2021)
  • Author(s): Joeselle M. Serrana, Bin Li, Tetsuya Sumi, Yasuhiro Takemon, Kozo Watanabe
  • Journal Title: Freshwater Biology Volume: 66 (11) Issue: 11 Pages: 2170-2184
  • DOI: 10.1111/fwb.13824
  • Peer Reviewed / Open Access
• [Journal Article] Next Generation of AMR Network (2021)
  • Author(s): Payumo, J. G., E. Alocilja, C. Boodoo, K. Luchini-Colbry, P. Ruegg, E. Mclamore, D. V. Gamboa, R. K. Briceno, A. Castaneda-Sabogal, K. Watanabe, M. J. Gordoncillo, D. Amalin, L. Fernando, and N. Bhusal
  • Journal Title: Encyclopedia Volume: 1 (3) Issue: 3 Pages: 871-892
  • DOI: 10.3390/encyclopedia1030067
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Updated research agenda for water, sanitation and antimicrobial resistance (2020)
  • Author(s): Daisuke Sano, Astrid Louse Wester, Heike Schmitt, Mohan Amarasiri, Amy Kirby, Kate Medlicott, Ana Maria de Roda Husman
  • Journal Title: Journal of Water and Health Volume: 18 Issue: 6 Pages: 858-868
  • DOI: 10.2166/wh.2020.033
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Editorial: bacterial antibiotic resistance in the water environment (2020)
  • Author(s): Gary Toranzos, Maronel Steyn, Tasha Santiago-Rodriguez, Daisuke Sano
  • Journal Title: Journal of Water and Health Volume: 18 Issue: 6 Pages: 855-857
  • DOI: 10.2166/wh.2020.002
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Complete Genome Sequence of Cellulase-Producing Microbulbifer sp. Strain GL-2, Isolated from Marine Fish Intestine (2020)
  • Author(s): Yuta Sugimoto, Ken-ichiro Ohnishi, Satoru Suzuki
  • Journal Title: Microbiology Resource Announcements Volume: 9 Issue: 32 Pages: 1-2
  • DOI: 10.1128/mra.00746-20
  • Peer Reviewed / Open Access
• [Journal Article] Tetracycline Resistance Gene Profiles in Red Seabream (Pagrus major) Intestine and Rearing Water After Oxytetracycline Administration (2020)
  • Author(s): Obayashi Yumiko、Kadoya Aya、Kataoka Naoto、Kanda Kazuki、Bak Su-Min、Iwata Hisato、Suzuki Satoru
  • Journal Title: Frontiers in Microbiology Volume: 11 Pages: 1764-1764
  • DOI: 10.3389/fmicb.2020.01764
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Biofilms: Hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism (2020)
  • Author(s): Kimihiro Abe, Nobuhiko Nomura, Satoru Suzuki
  • Journal Title: FEMS Microbiology Ecology Volume: 96(5) Issue: 5
  • DOI: 10.1093/femsec/fiaa031
  • NAID: 120007165469
  • Peer Reviewed / Open Access
• [Journal Article] Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered. (2019)
  • Author(s): Anomasiri, M., Sano D., Suzuki, S.
  • Journal Title: Crit. Rev. Environ. Sci. Technol. Volume: - Issue: 19 Pages: 1-44
  • DOI: 10.1080/10643389.2019.1692611
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] 海とワンヘルス: 水圏環境での薬剤耐性遺伝子のシンクとリンク (2023)
  • Author(s): 鈴木 聡
  • Organizer: 第57回日本水環境学会年会
  • Invited
• [Presentation] Dynamics of antibiotic resistance genes in water environments (2023)
  • Author(s): Satoru Suzuki
  • Organizer: THE 15TH MALAYSIA INTERNATIONAL GENETICS CONGRESS (MiGC15)
  • Int'l Joint Research / Invited
• [Presentation] 水産業関連の環境における薬剤耐性菌・耐性遺伝子の実態と対策 (2023)
  • Author(s): 鈴木 聡
  • Organizer: 97回日本感染症学会・71回日本化学療法学会合同学会
  • Invited
• [Presentation] Dynamics of antibiotic resistance genes in water environments (2023)
  • Author(s): Suzuki, S.
  • Organizer: THE 15TH MALAYSIA INTERNATIONAL GENETICS CONGRESS (MiGC15)
  • Int'l Joint Research / Invited
• [Presentation] 結合塩素による薬剤耐性遺伝子の接合伝達効率への影響評価 (2023)
  • Author(s): 森山桃子、Mohan Amarasiri、鈴木聡、佐野大輔
  • Organizer: 第57回日本水環境学会年会
• [Presentation] 過酢酸、過ギ酸による下水二次処理水中の細胞外薬剤耐性遺伝子の不活化評価 (2023)
  • Author(s): 小林大起、Mohan Amarasiri、古川隼士、佐野大輔、清和成
  • Organizer: 第57回日本水環境学会年会
• [Presentation] 水耕栽培野菜を介した薬剤耐性病原細菌による感染リスク評価モデルの構築 (2023)
  • Author(s): 高山峻、佐野大輔
  • Organizer: 第57回日本水環境学会年会
• [Presentation] 異なる環境条件での薬剤耐性遺伝子の伝達率の比較：個体群動態モデルの適用 (2023)
  • Author(s): 植田亮太、三浦郁修、阪本愛、門屋綾、鈴木聡、渡辺幸三
  • Organizer: 第57回日本水環境学会年会
• [Presentation] Circulation risk of antibiotic resistance genes via water environment (2022)
  • Author(s): Suzuki, S.
  • Organizer: International Seminar on One Health Towards Mosquito-Borne Disease Control and Antimicrobial Resistance
  • Int'l Joint Research / Invited
• [Presentation] Pay attention to “He has not lived that lives not after death” in antibiotic resistance issue (2022)
  • Author(s): Suzuki, S.
  • Organizer: 福岡県ワンヘルス国際フォーラム
  • Int'l Joint Research / Invited
• [Presentation] 海から考えるワンヘルス：薬剤耐性遺伝子の水環境での動態 (2022)
  • Author(s): 鈴木 聡
  • Organizer: 日本マリンエンジニアリング学会第3回海洋環境保全研究委員会
  • Invited
• [Presentation] Environmental factors that affect the conjugative transfer of antimicrobial resistance genes (2022)
  • Author(s): Moriyama, M., Suzuki, S., Sano, D.
  • Organizer: IWA World Water Congress & Exhibition 2022
  • Int'l Joint Research
• [Presentation] Spatio-temporal and Numerical Data Resolution Affect the Performance of Machine Learning in Dengue Forecast. A Case Study in Metropolitan Manila, Philippines. (2022)
  • Author(s): Francisco ME, Carvajal TM, Watanabe K
  • Organizer: International Seminar on Conducting Scientific Research - Ecological Approaches to Mosquito-borne Disease Control JSPS Core-to-Core Program B. Asia Africa Science Platforms
  • Int'l Joint Research / Invited
• [Presentation] Eco-epidemiology of Dengue Mosquitoes in Metropolitan Manila, Philippines (2022)
  • Author(s): Watanabe, K.
  • Organizer: Trinity University of Asia's Research Congress (TRIICON)
  • Int'l Joint Research / Invited
• [Presentation] Eco-epidemiology of Dengue Mosquitoes (2022)
  • Author(s): Watanabe, K.
  • Organizer: JSPS Core-to-core program "International Workshop on Ecological Approaches to Mosquito-borne Disease Control"
  • Int'l Joint Research / Invited
• [Presentation] Molecular biological approach to freshwater biodiversity research (2022)
  • Author(s): Watanabe, K.
  • Organizer: International seminar on Freshwater biodiversity, Antimicrobial resistance, and Fish immunology
  • Int'l Joint Research / Invited
• [Presentation] Urban Climate, Vector Mosquito and Dengue (2022)
  • Author(s): Watanabe, K.
  • Organizer: 3rd Symposium of JSPS Core-to-Core Program Symposium on Health Risk Assessment for Adaptation to Climate Change
  • Int'l Joint Research / Invited
• [Presentation] ワンヘルスと水圏環境 -薬剤耐性遺伝子のSINKとLINK- (2021)
  • Author(s): 鈴木 聡
  • Organizer: 第91回日本感染症学会西日本地方会学術集会 ・第64回日本感染症学会中日本地方会学術集会・第69回日本化学療法学会西日本支部総会合同学会
  • Invited
• [Presentation] Antimicrobial impact assessment: an ecological perspective (2021)
  • Author(s): Satoru Suzuki
  • Organizer: Antimicrobial Assessment on Global Aquaculture Production (AGAP) Workshop
  • Int'l Joint Research / Invited
• [Presentation] コロナ後の課題ー水環境の薬剤耐性菌 (2021)
  • Author(s): 鈴木 聡
  • Organizer: 第180回海洋フォーラム（疫病と海-コロナ禍での海とヒトの関係を考える）
  • Invited
• [Presentation] 虎は死して皮を残す：薬剤耐性遺伝子の環境での潜伏と動態 (2021)
  • Author(s): 鈴木 聡
  • Organizer: 第4回感染症診断と治療におけるゲノム解析
  • Invited
• [Presentation] Antimicrobial Resistance in Marine Environment (2021)
  • Author(s): Daisuke Sano
  • Organizer: Regional Conference in Civil Engineering & Sustainable Development Goal in Higher Education Institution
  • Int'l Joint Research / Invited
• [Presentation] Inactivation efficiency assessment of antimicrobial resistance genes (ARGs) existing as extracellular DNA using simple disinfection methods (2021)
  • Author(s): Hiroki Kobayashi, Mohan Amarasiri, Takashi Furukawa, Daisuke Sano, Kazunari Sei
  • Organizer: Water Environment and Technology Conference Online 2021（WET2021）
• [Presentation] 環境DNAとして存在する薬剤耐性遺伝子への簡易消毒による不活化効果の評価 (2021)
  • Author(s): 小林大起、Amarasiri Mohan、古川隼士、清和成、佐野大輔
  • Organizer: 第55回日本水環境学会年会
• [Presentation] 薬剤耐性遺伝子による生活環境の汚染に対するWASH介入効果の評価 (2021)
  • Author(s): 小沼千紘、Mohan Amarasiri、Sital Uprety、Thanh Nguyen、鈴木聡、佐野大輔
  • Organizer: 第55回日本水環境学会年会
• [Presentation] 水環境条件下における薬剤耐性遺伝子の接合伝達効率に関する研究, 学生ポスター発表賞（ライオン賞） (2021)
  • Author(s): 森山桃子、Mohan Amarasiri、鈴木聡、佐野大輔
  • Organizer: 第55回日本水環境学会年会
• [Presentation] 水環境サンプルからの形質転換可能な細胞外薬剤耐性遺伝子の回収方法の確立 (2020)
  • Author(s): 小沼千紘、アマラシリ モハン、鈴木聡、佐野大輔
  • Organizer: 第54回日本水環境学会年会（誌上発表）
• [Presentation] Ecological perspective of dissemination of antibiotic resistance genes. (2020)
  • Author(s): Satoru Suzuki
  • Organizer: International Symposium, Research Collaboration: Usable Science Resulting in Impact
  • Int'l Joint Research / Invited
• [Presentation] 環境関係：とくに水圏環境における薬剤耐性遺伝子の動態 (2020)
  • Author(s): 鈴木 聡
  • Organizer: 第69回日本感染症学会東日本地方学術集会・第67回日本化学療法学会東日本支部総会合同集会
  • Invited
• [Presentation] 環境細菌のもつ薬剤耐性遺伝子のヒト病原菌への伝播リスク (2020)
  • Author(s): 鈴木 聡
  • Organizer: 第54回緑膿菌感染症研究会
  • Invited
• [Book] Modernizing Global Health Security to Prevent, Detect, and Respond (2023)
  • Author(s): 1.Wang, S-H., Kebede, S., Abate, E., Amir, A., Calderon, E., Hoet, A.E., Ikram, A., Lejeune, J.T., Mekuria, Z., Suzuki, S., Grooters, S.V., Yimer, G., Gebreyes, W.A.
  • Total Pages: 570
  • Publisher: Elsevier
  • ISBN: 9780323909457
• [Book] 海とヒトの関係学4「疫病と海」 (2021)
  • Author(s): 鈴木 聡
  • Total Pages: 240
  • Publisher: 西日本出版社
  • ISBN: 9784908443596
• [Book] 海とヒトの関係学4「海と疫病」 (2021)
  • Author(s): 鈴木 聡
  • Total Pages: 240
  • Publisher: 西日本出版社
  • ISBN: 9784908443596