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Experimental and theoretical studies on the motion of single nanoparticles under localized external forces

Research Project

Project/Area Number 20H02067
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 19010:Fluid engineering-related
Research InstitutionKyoto University

Principal Investigator

Tsuji Tetsuro  京都大学, 情報学研究科, 准教授 (00708670)

Co-Investigator(Kenkyū-buntansha) 田口 智清  京都大学, 情報学研究科, 教授 (90448168)
Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2022: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2021: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2020: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Keywords分子流体力学 / ナノ粒子 / 光熱効果 / 光圧 / 熱泳動 / 履歴効果
Outline of Research at the Start

光や熱を利用した微小スケールの局在力場は,非接触な粒子操作方法として,近年生命科学への応用が進んでいる.一方,流体力学に着目した局在力場の適用は少なく,その利点を学理として体系化することが期待される.そこで本研究では,微小粒子運動を制御できる局在力場を用いて,単一粒子の運動を題材とした分子流体力学の基礎問題に実験・数理の両面から取り組む.理論・計算により精密解を構成しそれらを実験と比較することで,実験・数理の両面から分子流体力学の体系化に貢献する.得られた知見は,従来定量化が難しい粒子表面性状や流体局所物性の計測手法への展開が期待される.

Outline of Final Research Achievements

Recent advances in experiments have enabled the formation of micro- and nanoscale localized force fields using the localization of light and heat: the former and the latter are called optical pressure and thermophoretic force, respectively. These forces can be applied to the control of tiny objects. In this project, using the optical pressure of a focused laser and its conversion to heat, we realized the manipulation of tiny particles’ movement and proposed a method to clarify the origin of force. To be more specific, we developed a method for switching the accumulation and depletion of particles via the change of balance between thermal-convection-induced drag force and thermophoretic force. Furthermore, we proposed a technique to evaluate microflows that trigger thermophoresis. In the case of a gas, we also investigated the forces acting on a single tiny rotating particle using analytical and numerical approaches, preparing a setup for comparisons with experimental observations.

Academic Significance and Societal Importance of the Research Achievements

【学術的意義】真空中を除いて微小粒子は常に流体と接しているため,粒子に働く種々の力の起源を実験的に調べる上で熱流体力学的な力の理解は重要であり,分野を超えた学術的意義をもつ.本研究では,粒子表面近傍に誘起される流れの評価手法を提案し,この流れが粒子に力を及ぼすことを実験的に示すことで,手法の有用性を確かめた.【社会的意義】微小粒子に働く力の起源が分かれば,それを制御できる可能性が拓ける.空気中であればウイルスを含んだ飛沫,液体中であれば血液中の腫瘍マーカー等,識別と抽出が重要と考えられているさまざまな微小粒子に対して,本研究は新しい基盤分離技術の原理提案に繋がる基礎研究である.

Report

(4 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • Research Products

    (63 results)

All 2023 2022 2021 2020 Other

All Journal Article (13 results) (of which Peer Reviewed: 10 results,  Open Access: 7 results) Presentation (49 results) (of which Int'l Joint Research: 13 results,  Invited: 14 results) Remarks (1 results)

  • [Journal Article] 円板を過ぎる希薄流の数値解析:特性線法による運動論的方程式へのアプローチ2023

    • Author(s)
      富田卓磨,田口智清,辻徹郎
    • Journal Title

      京都大学工学研究科高等研究院・第 5 回先端流体理工学研究部門公開セミナー講演要旨集

      Volume: - Pages: 58-65

    • Related Report
      2022 Annual Research Report
  • [Journal Article] 特性線法を用いた分子気体流れの解析2023

    • Author(s)
      辻徹郎
    • Journal Title

      日本計算数理工学会・計算数理工学レビュー

      Volume: 2023-1 Pages: 9-18

    • Related Report
      2022 Annual Research Report
  • [Journal Article] A simple model for laser-induced thermal convection in a microchannel2023

    • Author(s)
      S. Saito, T. Tsuji, and S. Taguchi,
    • Journal Title

      Proc. SPIE

      Volume: -

    • Related Report
      2022 Annual Research Report
  • [Journal Article] Inverse Magnus effect in a rarefied gas2023

    • Author(s)
      Satoshi Taguchi and Tetsuro Tsuji
    • Journal Title

      Springer Proceedings

      Volume: -

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optical trapping in micro- and nanoconfinement systems: Role of thermo-fluid dynamics and applications2022

    • Author(s)
      Tsuji Tetsuro、Doi Kentaro、Kawano Satoyuki
    • Journal Title

      Journal of Photochemistry and Photobiology C: Photochemistry Reviews

      Volume: 52 Pages: 100533-100533

    • DOI

      10.1016/j.jphotochemrev.2022.100533

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] One-way flow over uniformly heated U-shaped bodies driven by thermal edge effects2022

    • Author(s)
      Taguchi Satoshi、Tsuji Tetsuro
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 1-17

    • DOI

      10.1038/s41598-022-05534-y

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inversion of the transverse force on a spinning sphere moving in a rarefied gas2021

    • Author(s)
      Taguchi Satoshi、Tsuji Tetsuro
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 933 Pages: 1-51

    • DOI

      10.1017/jfm.2021.1048

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Switching between Laser‐Induced Thermophoresis and Thermal Convection of Liquid Suspension in a Microgap with Variable Dimension2021

    • Author(s)
      Tetsuro Tsuji, Satoshi Taguchi and Hiroki Takamatsu
    • Journal Title

      ELECTROPHORESIS

      Volume: 42 Issue: 21-22 Pages: 2401-2409

    • DOI

      10.1002/elps.202100118

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fluid convection driven by suspended particles in optical trapping2021

    • Author(s)
      Tetsuro Tsuji, Chie Hosokawa, Tatsunori Kishimoto, Takumi Okubo, Suguru N. Kudoh, and Satoyuki Kawano
    • Journal Title

      Proceedings of SPIE

      Volume: 11926 Pages: 1-2

    • DOI

      10.1117/12.2616108

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Transient behaviour of a rarefied gas around a sphere caused by impulsive rotation2021

    • Author(s)
      S. Taguchi, T. Tsuji, and M. Kotera
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 909

    • DOI

      10.1017/jfm.2020.907

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A generalized slip-flow theory for a slightly rarefied gas flow induced by discontinuous wall temperature2021

    • Author(s)
      S. Taguchi and T. Tsuji
    • Journal Title

      Springer INdAM Series

      Volume: in press

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synchronized resistive-pulse analysis with flow visualization for single micro- and nanoscale objects driven by optical vortex in double orifice2021

    • Author(s)
      K. Nakajima, R. Nakatsuka, T. Tsuji, K. Doi, and S. Kawano
    • Journal Title

      Scientific Reports

      Volume: in press

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] On the motion of slightly rarefied gas induced by a discontinuous surface temperature2020

    • Author(s)
      S. Taguchi and T. Tsuji
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 897

    • DOI

      10.1017/jfm.2020.332

    • NAID

      120006870333

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Presentation] 光圧の分子流体科学への展開2023

    • Author(s)
      辻徹郎
    • Organizer
      新学術領域研究「光圧ナノ物質操作」若手領域会議
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 光と熱を用いた微小物質操作に関する実験とモデル化2023

    • Author(s)
      辻徹郎
    • Organizer
      生物とソフトマターに関する理論とシミュレーションについての研究会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 光熱変換の分子流体力学への展開2023

    • Author(s)
      辻徹郎
    • Organizer
      第 70 回応用物理学会春季学術講演会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 特性線法を用いた分子気体流れの解析2023

    • Author(s)
      辻徹郎
    • Organizer
      第 43 回計算数理工学フォーラム
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 円板を過ぎる希薄流の数値解析:特性線法による運動論的方程式へのアプローチ2023

    • Author(s)
      富田卓磨,田口智清,辻徹郎
    • Organizer
      第 5 回先端流体理工学研究部門公開セミナー
    • Related Report
      2022 Annual Research Report
  • [Presentation] 光ピンセットされたトレーサーによるマイクロ流れの可視化2023

    • Author(s)
      梅世哲,辻徹郎,田口智清
    • Organizer
      第 17 回 ICT イノベーション
    • Related Report
      2022 Annual Research Report
  • [Presentation] 希薄気体流の剛体球分子動力学シミュレーション2023

    • Author(s)
      清瀬遼,田口智清,辻徹郎
    • Organizer
      シンポジウム:先端数理科学の目指すもの ―現象にかかわる「理」を理解する―
    • Related Report
      2022 Annual Research Report
  • [Presentation] 気体中の微粒子まわりの流れにおける非線形効果2023

    • Author(s)
      龍溪優希,田口智清,辻徹郎
    • Organizer
      シンポジウム:先端数理科学の目指すもの ―現象にかかわる「理」を理解する―
    • Related Report
      2022 Annual Research Report
  • [Presentation] 集光レーザーによるマイクロ流路内の熱対流の解析2023

    • Author(s)
      齊藤駿,辻徹郎,田口智清
    • Organizer
      シンポジウム:先端数理科学の目指すもの ―現象にかかわる「理」を理解する―
    • Related Report
      2022 Annual Research Report
  • [Presentation] Numerical analysis of unsteady rarefied gas flows around a sphere induced by impulsive rotation2022

    • Author(s)
      T. Tsuji, S. Taguchi, and M. Kotera
    • Organizer
      The 32th International Symposium on Rarefied Gas Dynamics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optothermal manipulation of particles in microfluidic systems2022

    • Author(s)
      T. Tsuji
    • Organizer
      Japan-France Joint Workshop "Interacting Particle Systems and Fluid Mechanics: Theory and Applications"
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 光熱効果により誘起される熱泳動と熱対流の共存状態における流路高さの影響2022

    • Author(s)
      辻徹郎,田口智清,髙松宏基
    • Organizer
      日本機械学会年次大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 熱泳動を用いた微小粒子輸送に関する実験および数理的研究2022

    • Author(s)
      辻徹郎
    • Organizer
      日本流体力学会年会 2022
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Modeling and experiments on thermophoresis in microfluidic systems2022

    • Author(s)
      辻徹郎
    • Organizer
      日本航空宇宙学会関西支部分科会「非平衡流体への運動学的アプローチ」(第 9 回)
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Source-sink-type condition for slightly rarefied gas flow driven by a discontinuous wall temperature2022

    • Author(s)
      S. Taguchi and T. Tsuji
    • Organizer
      The 32th International Symposium on Rarefied Gas Dynamics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Numerical analysis of slow uniform flow past a circular disk by using the method of characteristics2022

    • Author(s)
      T. Tomita, S. Taguchi, and T. Tsuji
    • Organizer
      The 32th International Symposium on Rarefied Gas Dynamics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Numerical Analysis of a Slow Rarefied Gas Flow past a Circular Disk2022

    • Author(s)
      T. Tomita, S. Taguchi, T. Tsuji
    • Organizer
      The 15th World Congress on Computational Mechanics (WCCM-XV)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 熱尖端効果と U 字型物体列を利用した一方向流れ2022

    • Author(s)
      田口智清,辻徹郎
    • Organizer
      日本流体力学会年会 2022
    • Related Report
      2022 Annual Research Report
  • [Presentation] 温度勾配によって生じるマイクロ粒子周りの流れの可視化手法の検討2022

    • Author(s)
      梅世哲,辻徹郎,田口智清
    • Organizer
      第 13 回マイクロ・ナノ工学シンポジウム
    • Related Report
      2022 Annual Research Report
  • [Presentation] 希薄気体中の球に働くマグナス力とその反転2022

    • Author(s)
      田口智清,辻徹郎
    • Organizer
      第4回先端流体理工学研究部門公開セミナー
    • Related Report
      2021 Annual Research Report
  • [Presentation] ボルツマン方程式における分子無秩序の仮定の数値的検証2022

    • Author(s)
      清瀬遼,田口智清,辻徹郎
    • Organizer
      第16回ICTイノベーション
    • Related Report
      2021 Annual Research Report
  • [Presentation] 円板を過ぎるマイクロ気体流2022

    • Author(s)
      富田卓磨,田口智清,辻徹郎
    • Organizer
      第16回ICTイノベーショ ン
    • Related Report
      2021 Annual Research Report
  • [Presentation] Transient rarefied gas flow around a sphere induced by an abrupt onset of self-rotation2022

    • Author(s)
      T. Tsuji
    • Organizer
      Analysis Seminar in Institute of Mathematics, Academia Sinica
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Slip-flow theory for a slightly rarefied gas with a discontinuous boundary data2022

    • Author(s)
      S. Taguchi
    • Organizer
      Analysis Seminar in Institute of Mathematics, Academia Sinica
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Magnus effect in rarefied gas2022

    • Author(s)
      S. Taguchi
    • Organizer
      JSPS/SAC SEMINAR nn Gas Kinetic/dynamics and Life Science
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Fluid convection driven by suspended particles in optical trapping2021

    • Author(s)
      T. Tsuji, C. Hosokawa, T. Kishimoto, T. Okubo, S.N. Kudoh, and S. Kawano
    • Organizer
      The 8th Optical Manipulation and Structured Materials Conference
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Role of fluid dynamics in optical trapping2021

    • Author(s)
      T. Tsuji
    • Organizer
      The 2nd Joint Meeting of The European Society for Clinical Hemorheology and Microcirculation, The International Society for Clinical Hemorheology, and The International Society of Biorheology
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Numerical analysis of a rarefied gas flow around a sphere caused by impulsive rotation2021

    • Author(s)
      T. Tsuji
    • Organizer
      International Workshop: Recent Advances in Kinetic Theory and Non-Equilibrium Fluid Dynamics
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 温度差が駆動する微小物質の輸送2021

    • Author(s)
      辻徹郎
    • Organizer
      第3回先進的ながれ研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] マイクロ・ナノ粒子の熱泳動現象の理解と応用に向けたいくつかの試み2021

    • Author(s)
      辻徹郎
    • Organizer
      日本伝熱学会関西支部第 28 期第 2 回講演討論会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 微小粒子の光捕捉過程にともなう流れ場の解析2021

    • Author(s)
      辻徹郎,細川千絵,岸本龍典,大久保匠,工藤卓,川野聡恭
    • Organizer
      日本機械学会年次大会2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 局所的な光と熱の効果を利用した微小粒子の操作について2021

    • Author(s)
      辻徹郎
    • Organizer
      第49回可視化情報シンポジウム
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 集光レーザーにより誘起される熱泳動と熱対流の共存状態に対する流路高さの影響2021

    • Author(s)
      辻徹郎,田口智清,髙松宏基
    • Organizer
      日本流体力学会年会 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 光を用いた物質操作における熱と流れの役割2021

    • Author(s)
      辻徹郎
    • Organizer
      物質・デバイス領域共同研究セミナー「光駆動物質輸送の新展開」
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 物質の光圧操作における周囲流体の影響について2021

    • Author(s)
      辻徹郎
    • Organizer
      第 8 回光マニピュレーション研究会(第 18 回光圧コロキウム)
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 円板を過ぎる中程度に希薄な流れ:モデル Boltzmann 方程式の数値解析2021

    • Author(s)
      富田卓磨,田口智清,辻徹郎
    • Organizer
      日本流体力学会年会 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] 球の突発的な回転が引き起こす気体の非定常応答2021

    • Author(s)
      田口智清,辻徹郎,小寺雅司
    • Organizer
      日本流体力学会年会 2021
    • Related Report
      2021 Annual Research Report
  • [Presentation] Slip flow theory for a rarefied gas flow driven by a discontinuous wall temperature2021

    • Author(s)
      S. Taguchi
    • Organizer
      International Workshop: Recent Advances in Kinetic Theory and Non-Equilibrium Fluid Dynamics
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 流体中の温度勾配に駆動されるマイクロ・ナノ粒子の運動2021

    • Author(s)
      辻徹郎
    • Organizer
      第 3 回先端流体理工学研究部門公開セミナー
    • Related Report
      2020 Annual Research Report
  • [Presentation] 温度差が駆動する微小物質の輸送2021

    • Author(s)
      辻徹郎
    • Organizer
      シンポジム:先端数理科学の目指すもの―現象にかかわる「理」ことわりを理解する―
    • Related Report
      2020 Annual Research Report
  • [Presentation] 松原湧汰,田口智清,辻徹郎2021

    • Author(s)
      気体中のマイクロスケール球状液滴に働く抵抗
    • Organizer
      第 15 回 ICT イノベーション
    • Related Report
      2020 Annual Research Report
  • [Presentation] Numerical analysis of a rarefied gas flow around a sphere induced by an abrupt onset of self-rotation2021

    • Author(s)
      T. Tsuji
    • Organizer
      JSPS/SAC meeting
    • Related Report
      2020 Annual Research Report
  • [Presentation] Numerical simulation of micro- and nanoparticles orbital motion driven by an optical vortex2020

    • Author(s)
      T. Tsuji and S. Kawano
    • Organizer
      The 7th Optical Manipulation and Structured Materials Conference
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 微小粒子の光捕捉過程における周囲流体の大規模流れ2020

    • Author(s)
      辻徹郎,細川千絵,岸本龍典,大久保匠,工藤卓,川野聡恭
    • Organizer
      第81回応用物理学会秋季学術講演会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 光渦を用いたナノ粒子操作に おける流体力学的粒子間相互作用の影響2020

    • Author(s)
      辻徹郎,中塚遼治,中島吉太郎,土井謙太郎,川野聡恭
    • Organizer
      日本機械学会年次大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 微小粒子の集団的公転運動における流体力学的相互作用の影響2020

    • Author(s)
      辻徹郎,中塚遼治,中島吉太郎,土井謙太郎,川野聡恭
    • Organizer
      日本流体力学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 希薄気体中の球に対する非線形熱伝達問題2020

    • Author(s)
      山崎悠斗,田口智清,辻徹郎
    • Organizer
      日本流体力学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 弱希薄気体中の球状液滴に働く抵抗:液滴の内部流動の影響2020

    • Author(s)
      松原湧汰,田口智清,辻徹郎
    • Organizer
      日本流体力学会年会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 弱希薄気体の低 Reynolds 数領域における数値解析2020

    • Author(s)
      俣賀幹夫,田口智清,辻徹郎
    • Organizer
      第 34 回数値流体力学シンポジウム
    • Related Report
      2020 Annual Research Report
  • [Remarks] 研究代表者ホームページ

    • URL

      https://tetsurotsuji.com/

    • Related Report
      2020 Annual Research Report

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Published: 2020-04-28   Modified: 2025-01-30  

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