| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2022: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2021: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2020: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Outline of Final Research Achievements |
The aim of this study was to develop glomerular and tubular models by 2- or 3-dimensional co-culture of human kidney-derived cells in a microfluidic device. Using the fabricated device, we optimized the culture conditions for kidney-derived cells by investigating different culture conditions. In addition, the characteristics of the models were clarified for the model in which shear stress due to medium flow was applied and for the disease model constructed by applying disease-inducing factors to the normal model.
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