| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2023: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2022: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2021: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2020: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
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| Outline of Final Research Achievements |
Surface potential is one of the important factors affecting the functionality of the interfaces. In this study, model interfaces were systematically prepared by controlled radical polymerization to investigate the electrophoretic behavior and interaction to biomolecules and cells. For the cationic polymer brushes possessing quaternary ammonium moiety, the equation for the solid surface was suited, and interaction to protein was regulated by the electrostatic interaction. The interaction analysis to bacteria suggested that initial adsorption of bacteria on the high-graft-density polymer brush strongly interacted compared to that of the low-graft-density polymer brush. This result was considered to involve in the bactericidal ability. Thus, structure-property relation for polymer materials and precise interaction analysis indicated the mechanism for bactericidal materials.
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