| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2022: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2021: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2020: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Outline of Final Research Achievements |
(1) It was revealed that the novel selenium protein of Geobacter sp. is a sulfur-reducing enzyme, and its X-ray crystal structure was determined. (2) Investigation of the growth of Cellulomonas sp. suggested their utilization of selenite as the final electron acceptor. (3) Research on the mechanism of extracellular selenium nanoparticle formation in Escherichia coli revealed that E. coli forms selenium nanoparticles and releases them into the extracellular environment. The importance of the cell membrane was also suggested. (4) Nutritional analysis of extracellular selenium nanoparticles was conducted. Administration of selenium nanoparticles derived from E. coli to selenium-deficient rats evaluated the biological utilization of selenium, and it was demonstrated that the utilization efficiency of selenium nanoparticles from E. coli was low.
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